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***  SECYEG_ITASSER_HDS_HIS_31  ***

CA strain for 260811202712365370

---  normal mode 12  ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA iCA i+1vari
MET 1ASN 2 0.0000
ASN 2VAL 3 -0.0004
VAL 3GLY 4 0.0002
GLY 4ALA 5 -0.0008
ALA 5ARG 6 0.0002
ARG 6GLY 7 -0.0004
GLY 7ASN 8 -0.0001
ASN 8ALA 9 -0.0015
ALA 9GLY 10 -0.0002
GLY 10LEU 11 -0.0000
LEU 11PHE 12 0.0004
PHE 12TRP 13 0.0037
TRP 13ARG 14 0.0003
ARG 14PHE 15 0.0003
PHE 15GLY 16 0.0001
GLY 16PHE 17 0.0059
PHE 17THR 18 -0.0000
THR 18LEU 19 0.0001
LEU 19LEU 20 0.0003
LEU 20ALA 21 0.0031
ALA 21LEU 22 -0.0001
LEU 22ILE 23 0.0000
ILE 23VAL 24 0.0001
VAL 24TYR 25 -0.0008
TYR 25ARG 26 0.0002
ARG 26LEU 27 0.0004
LEU 27GLY 28 0.0002
GLY 28THR 29 -0.0084
THR 29TYR 30 -0.0001
TYR 30ILE 31 0.0001
ILE 31PRO 32 -0.0002
PRO 32ILE 33 0.0017
ILE 33PRO 34 0.0000
PRO 34GLY 35 0.0002
GLY 35VAL 36 0.0001
VAL 36ASN 37 -0.0010
ASN 37PRO 38 0.0001
PRO 38SER 39 0.0001
SER 39VAL 40 -0.0002
VAL 40VAL 41 0.0025
VAL 41GLU 42 -0.0001
GLU 42ASP 43 0.0005
ASP 43ILE 44 0.0001
ILE 44ILE 45 0.0099
ILE 45SER 46 0.0002
SER 46SER 47 0.0001
SER 47HIS 48 -0.0000
HIS 48ALA 49 -0.0014
ALA 49THR 50 0.0001
THR 50GLY 51 0.0002
GLY 51VAL 52 -0.0003
VAL 52LEU 53 -0.0062
LEU 53GLY 54 -0.0002
GLY 54ILE 55 -0.0005
ILE 55PHE 56 0.0001
PHE 56ASN 57 -0.0011
ASN 57VAL 58 0.0006
VAL 58PHE 59 -0.0000
PHE 59SER 60 -0.0001
SER 60GLY 61 0.0000
GLY 61GLY 62 0.0002
GLY 62ALA 63 0.0001
ALA 63LEU 64 -0.0001
LEU 64GLY 65 -0.0056
GLY 65ARG 66 0.0000
ARG 66MET 67 0.0005
MET 67THR 68 -0.0000
THR 68ILE 69 -0.0004
ILE 69PHE 70 0.0001
PHE 70ALA 71 0.0003
ALA 71LEU 72 -0.0003
LEU 72ASN 73 0.0019
ASN 73VAL 74 -0.0000
VAL 74MET 75 0.0001
MET 75PRO 76 -0.0003
PRO 76TYR 77 -0.0050
TYR 77ILE 78 0.0002
ILE 78VAL 79 -0.0002
VAL 79SER 80 -0.0001
SER 80SER 81 -0.0110
SER 81ILE 82 -0.0000
ILE 82ILE 83 0.0000
ILE 83VAL 84 -0.0001
VAL 84GLN 85 -0.0201
GLN 85LEU 86 0.0000
LEU 86LEU 87 -0.0003
LEU 87SER 88 -0.0004
SER 88VAL 89 0.0062
VAL 89ALA 90 0.0001
ALA 90ILE 91 0.0000
ILE 91PRO 92 0.0002
PRO 92THR 93 -0.0060
THR 93LEU 94 0.0002
LEU 94ASN 95 -0.0004
ASN 95GLU 96 -0.0004
GLU 96MET 97 -0.0039
MET 97ARG 98 0.0002
ARG 98GLN 99 0.0001
GLN 99ASP 100 -0.0000
ASP 100GLY 101 -0.0110
GLY 101GLU 102 -0.0001
GLU 102LEU 103 -0.0002
LEU 103GLY 104 0.0001
GLY 104ARG 105 -0.0022
ARG 105MET 106 0.0001
MET 106LYS 107 0.0004
LYS 107MET 108 -0.0002
MET 108SER 109 -0.0020
SER 109THR 110 -0.0003
THR 110TYR 111 0.0002
TYR 111THR 112 -0.0001
THR 112ARG 113 -0.0050
ARG 113TYR 114 0.0001
TYR 114LEU 115 -0.0000
LEU 115SER 116 -0.0001
SER 116VAL 117 -0.0154
VAL 117ALA 118 0.0001
ALA 118PHE 119 -0.0001
PHE 119CYS 120 -0.0002
CYS 120ILE 121 -0.0167
ILE 121ALA 122 0.0000
ALA 122GLN 123 -0.0002
GLN 123GLY 124 -0.0003
GLY 124LEU 125 -0.0034
LEU 125VAL 126 -0.0000
VAL 126ILE 127 0.0004
ILE 127LEU 128 -0.0003
LEU 128LEU 129 0.0008
LEU 129GLY 130 -0.0002
GLY 130LEU 131 0.0002
LEU 131GLU 132 -0.0002
GLU 132ARG 133 0.0001
ARG 133MET 134 -0.0001
MET 134ASN 135 0.0004
ASN 135SER 136 -0.0001
SER 136ASP 137 0.0032
ASP 137GLU 138 -0.0003
GLU 138VAL 139 -0.0001
VAL 139MET 140 0.0000
MET 140VAL 141 0.0023
VAL 141VAL 142 0.0003
VAL 142ILE 143 0.0002
ILE 143ASN 144 -0.0001
ASN 144PRO 145 -0.0021
PRO 145GLY 146 -0.0001
GLY 146ILE 147 0.0003
ILE 147MET 148 0.0003
MET 148PHE 149 0.0018
PHE 149ARG 150 -0.0001
ARG 150VAL 151 0.0003
VAL 151VAL 152 -0.0002
VAL 152GLY 153 -0.0016
GLY 153ILE 154 -0.0002
ILE 154SER 155 -0.0001
SER 155SER 156 0.0001
SER 156LEU 157 -0.0041
LEU 157LEU 158 0.0000
LEU 158ALA 159 0.0004
ALA 159GLY 160 -0.0004
GLY 160THR 161 -0.0039
THR 161MET 162 -0.0002
MET 162PHE 163 -0.0001
PHE 163LEU 164 0.0004
LEU 164LEU 165 -0.0003
LEU 165TRP 166 -0.0002
TRP 166LEU 167 0.0002
LEU 167GLY 168 0.0005
GLY 168GLU 169 0.0076
GLU 169ARG 170 0.0003
ARG 170ILE 171 0.0001
ILE 171ASN 172 -0.0000
ASN 172ALA 173 0.0154
ALA 173LYS 174 -0.0002
LYS 174GLY 175 -0.0002
GLY 175ILE 176 0.0003
ILE 176GLY 177 0.0108
GLY 177ASN 178 -0.0001
ASN 178GLY 179 0.0000
GLY 179ILE 180 0.0002
ILE 180SER 181 -0.0111
SER 181LEU 182 -0.0002
LEU 182ILE 183 -0.0002
ILE 183ILE 184 -0.0001
ILE 184PHE 185 -0.0036
PHE 185VAL 186 -0.0002
VAL 186GLY 187 -0.0001
GLY 187ILE 188 0.0002
ILE 188ILE 189 -0.0019
ILE 189SER 190 0.0000
SER 190GLU 191 0.0002
GLU 191LEU 192 -0.0001
LEU 192PRO 193 0.0041
PRO 193SER 194 0.0002
SER 194SER 195 0.0002
SER 195ILE 196 0.0002
ILE 196SER 197 0.0014
SER 197SER 198 -0.0001
SER 198VAL 199 -0.0001
VAL 199PHE 200 0.0002
PHE 200LEU 201 0.0018
LEU 201LEU 202 0.0001
LEU 202GLY 203 0.0001
GLY 203LYS 204 0.0005
LYS 204ASN 205 -0.0020
ASN 205GLY 206 -0.0001
GLY 206GLU 207 0.0002
GLU 207VAL 208 -0.0000
VAL 208SER 209 -0.0052
SER 209GLY 210 -0.0000
GLY 210LEU 211 0.0002
LEU 211VAL 212 0.0002
VAL 212VAL 213 -0.0009
VAL 213LEU 214 -0.0000
LEU 214SER 215 -0.0003
SER 215MET 216 -0.0004
MET 216LEU 217 -0.0102
LEU 217LEU 218 0.0002
LEU 218ALA 219 0.0002
ALA 219PHE 220 -0.0002
PHE 220PHE 221 0.0086
PHE 221ALA 222 -0.0001
ALA 222LEU 223 0.0002
LEU 223PHE 224 0.0001
PHE 224LEU 225 0.0149
LEU 225LEU 226 -0.0000
LEU 226ILE 227 -0.0000
ILE 227ILE 228 0.0002
ILE 228PHE 229 0.0190
PHE 229PHE 230 -0.0001
PHE 230GLU 231 0.0001
GLU 231ARG 232 -0.0000
ARG 232SER 233 -0.0011
SER 233TYR 234 -0.0001
TYR 234ARG 235 0.0003
ARG 235LYS 236 -0.0003
LYS 236VAL 237 0.0730
VAL 237PHE 238 0.0001
PHE 238VAL 239 -0.0002
VAL 239GLN 240 -0.0001
GLN 240TYR 241 0.0423
TYR 241PRO 242 -0.0000
PRO 242LYS 243 0.0003
LYS 243ARG 244 0.0000
ARG 244GLN 245 0.0024
GLN 245THR 246 -0.0000
THR 246GLY 247 0.0001
GLY 247GLY 248 -0.0003
GLY 248ARG 249 -0.0126
ARG 249PHE 250 -0.0003
PHE 250TYR 251 0.0003
TYR 251ASN 252 0.0005
ASN 252SER 253 0.0251
SER 253ASP 254 -0.0002
ASP 254SER 255 0.0003
SER 255SER 256 -0.0001
SER 256TYR 257 0.1179
TYR 257ILE 258 -0.0002
ILE 258PRO 259 0.0000
PRO 259LEU 260 0.0004
LEU 260LYS 261 0.0818
LYS 261ILE 262 -0.0002
ILE 262ASN 263 -0.0001
ASN 263THR 264 -0.0000
THR 264ALA 265 0.0195
ALA 265GLY 266 -0.0002
GLY 266VAL 267 -0.0003
VAL 267ILE 268 -0.0000
ILE 268PRO 269 0.0191
PRO 269PRO 270 -0.0000
PRO 270ILE 271 -0.0000
ILE 271PHE 272 -0.0000
PHE 272ALA 273 0.0029
ALA 273ASN 274 -0.0002
ASN 274ALA 275 0.0001
ALA 275LEU 276 -0.0003
LEU 276LEU 277 0.0087
LEU 277LEU 278 -0.0001
LEU 278SER 279 -0.0001
SER 279SER 280 -0.0001
SER 280ILE 281 -0.0013
ILE 281SER 282 -0.0001
SER 282LEU 283 -0.0001
LEU 283VAL 284 -0.0000
VAL 284ARG 285 -0.0049
ARG 285PHE 286 0.0003
PHE 286HIS 287 0.0001
HIS 287SER 288 -0.0000
SER 288GLY 289 -0.0045
GLY 289SER 290 0.0002
SER 290GLU 291 -0.0001
GLU 291TRP 292 0.0001
TRP 292ALA 293 0.0011
ALA 293ASP 294 0.0003
ASP 294VAL 295 0.0003
VAL 295LEU 296 0.0001
LEU 296LEU 297 -0.0007
LEU 297ARG 298 0.0002
ARG 298TYR 299 0.0001
TYR 299LEU 300 -0.0001
LEU 300SER 301 -0.0017
SER 301SER 302 -0.0001
SER 302GLU 303 0.0002
GLU 303GLY 304 0.0002
GLY 304ILE 305 0.0189
ILE 305LEU 306 -0.0001
LEU 306TYR 307 -0.0000
TYR 307VAL 308 -0.0002
VAL 308SER 309 0.0094
SER 309VAL 310 0.0001
VAL 310TYR 311 0.0002
TYR 311ILE 312 0.0001
ILE 312ALA 313 0.0089
ALA 313LEU 314 0.0002
LEU 314ILE 315 -0.0000
ILE 315MET 316 0.0001
MET 316PHE 317 -0.0090
PHE 317PHE 318 -0.0002
PHE 318THR 319 -0.0002
THR 319PHE 320 -0.0000
PHE 320PHE 321 0.0038
PHE 321TYR 322 0.0002
TYR 322THR 323 -0.0002
THR 323SER 324 0.0001
SER 324LEU 325 0.0084
LEU 325VAL 326 0.0003
VAL 326PHE 327 -0.0001
PHE 327ASP 328 -0.0002
ASP 328THR 329 -0.0012
THR 329LYS 330 -0.0001
LYS 330GLU 331 0.0001
GLU 331THR 332 0.0002
THR 332SER 333 -0.0003
SER 333GLU 334 0.0001
GLU 334MET 335 0.0002
MET 335LEU 336 -0.0002
LEU 336LYS 337 0.0405
LYS 337LYS 338 0.0001
LYS 338ASN 339 0.0003
ASN 339GLY 340 -0.0002
GLY 340GLY 341 0.0344
GLY 341PHE 342 0.0002
PHE 342VAL 343 -0.0001
VAL 343PRO 344 -0.0001
PRO 344GLY 345 -0.0844
GLY 345LYS 346 -0.0001
LYS 346ARG 347 -0.0003
ARG 347PRO 348 -0.0002
PRO 348GLY 349 -0.0049
GLY 349LYS 350 -0.0000
LYS 350ALA 351 0.0001
ALA 351THR 352 0.0003
THR 352LYS 353 -0.0360
LYS 353GLU 354 -0.0002
GLU 354TYR 355 0.0004
TYR 355PHE 356 -0.0000
PHE 356ASP 357 -0.1160
ASP 357GLN 358 0.0001
GLN 358VAL 359 0.0003
VAL 359ILE 360 0.0001
ILE 360GLY 361 -0.0582
GLY 361ARG 362 0.0001
ARG 362ILE 363 0.0002
ILE 363THR 364 -0.0001
THR 364VAL 365 0.0249
VAL 365LEU 366 -0.0002
LEU 366GLY 367 -0.0002
GLY 367ALA 368 0.0001
ALA 368ILE 369 -0.0439
ILE 369TYR 370 0.0004
TYR 370LEU 371 -0.0001
LEU 371SER 372 -0.0002
SER 372VAL 373 -0.0215
VAL 373VAL 374 0.0002
VAL 374CYS 375 -0.0001
CYS 375VAL 376 0.0001
VAL 376VAL 377 -0.0066
VAL 377PRO 378 0.0000
PRO 378GLU 379 -0.0003
GLU 379ILE 380 0.0003
ILE 380VAL 381 0.0016
VAL 381ARG 382 0.0004
ARG 382HIS 383 0.0000
HIS 383TYR 384 -0.0004
TYR 384CYS 385 0.0011
CYS 385ALA 386 -0.0001
ALA 386VAL 387 -0.0000
VAL 387SER 388 0.0004
SER 388PHE 389 0.0058
PHE 389THR 390 -0.0003
THR 390LEU 391 0.0001
LEU 391GLY 392 0.0001
GLY 392GLY 393 0.0221
GLY 393THR 394 0.0001
THR 394SER 395 -0.0001
SER 395PHE 396 0.0001
PHE 396LEU 397 0.0076
LEU 397ILE 398 -0.0002
ILE 398ILE 399 -0.0001
ILE 399VAL 400 -0.0001
VAL 400ASN 401 0.0006
ASN 401VAL 402 -0.0000
VAL 402ILE 403 -0.0001
ILE 403ASN 404 -0.0001
ASN 404ASP 405 -0.0168
ASP 405THR 406 -0.0003
THR 406PHE 407 -0.0003
PHE 407SER 408 -0.0002
SER 408GLN 409 -0.0316
GLN 409VAL 410 0.0000
VAL 410GLN 411 -0.0003
GLN 411THR 412 0.0001
THR 412GLN 413 0.0008
GLN 413VAL 414 -0.0001
VAL 414TYR 415 0.0002
TYR 415SER 416 -0.0002
SER 416GLY 417 -0.0433
GLY 417ARG 418 0.0003
ARG 418TYR 419 0.0001
TYR 419SER 420 -0.0001
SER 420ALA 421 -0.0105
ALA 421LEU 422 -0.0001
LEU 422MET 423 0.0003
MET 423LYS 424 0.0003
LYS 424LYS 425 -0.0082
LYS 425SER 426 -0.0003
SER 426GLU 427 0.0001
GLU 427LEU 428 0.0004
LEU 428TRP 429 -0.0073
TRP 429LYS 430 -0.0004
LYS 430LYS 431 -0.0002
LYS 431VAL 432 -0.0001
VAL 432LYS 433 -0.0016
LYS 433MET 1 0.0016
MET 1PHE 2 0.0000
PHE 2LEU 3 -0.0002
LEU 3ALA 4 0.0000
ALA 4MET 5 0.0302
MET 5ILE 6 0.0002
ILE 6GLY 7 -0.0002
GLY 7SER 8 -0.0004
SER 8PHE 9 0.1965
PHE 9ALA 10 -0.0001
ALA 10ARG 11 0.0001
ARG 11PHE 12 0.0001
PHE 12LEU 13 0.0033
LEU 13CYS 14 -0.0001
CYS 14ASP 15 -0.0001
ASP 15VAL 16 -0.0004
VAL 16LYS 17 0.0123
LYS 17GLN 18 -0.0001
GLN 18GLU 19 -0.0002
GLU 19ALA 20 -0.0003
ALA 20LEU 21 0.0399
LEU 21GLN 22 0.0003
GLN 22VAL 23 -0.0001
VAL 23SER 24 0.0001
SER 24TRP 25 0.0694
TRP 25ALA 26 0.0000
ALA 26SER 27 0.0001
SER 27ARG 28 0.0001
ARG 28LYS 29 -0.0070
LYS 29GLU 30 0.0000
GLU 30VAL 31 -0.0002
VAL 31SER 32 -0.0001
SER 32VAL 33 -0.0072
VAL 33PHE 34 0.0000
PHE 34LEU 35 -0.0000
LEU 35LEU 36 -0.0001
LEU 36ILE 37 -0.0157
ILE 37VAL 38 0.0000
VAL 38LEU 39 -0.0001
LEU 39LEU 40 0.0000
LEU 40THR 41 0.0041
THR 41VAL 42 0.0001
VAL 42VAL 43 0.0005
VAL 43VAL 44 -0.0001
VAL 44SER 45 -0.0027
SER 45SER 46 0.0001
SER 46ILE 47 -0.0001
ILE 47LEU 48 0.0002
LEU 48PHE 49 0.0072
PHE 49SER 50 -0.0002
SER 50CYS 51 -0.0003
CYS 51VAL 52 -0.0001
VAL 52ASP 53 0.0027
ASP 53PHE 54 -0.0001
PHE 54VAL 55 -0.0003
VAL 55PHE 56 -0.0001
PHE 56LEU 57 0.0037
LEU 57ARG 58 0.0004
ARG 58LEU 59 0.0002
LEU 59VAL 60 0.0004
VAL 60LYS 61 -0.0019
LYS 61ILE 62 -0.0000
ILE 62ALA 63 0.0000
ALA 63LEU 64 -0.0003
LEU 64GLY 65 0.0016
GLY 65VAL 66 -0.0003
VAL 66VAL 67 -0.0002
VAL 67TYR 68 -0.0000
TYR 68ALA 69 0.0008
ALA 69ALA 70 -0.0002
ALA 70MET 1 -0.0029
MET 1SER 2 -0.0001
SER 2PHE 3 -0.0002
PHE 3VAL 4 -0.0002
VAL 4SER 5 -0.0039
SER 5CYS 6 0.0003
CYS 6LEU 7 0.0003
LEU 7MET 8 0.0000
MET 8PHE 9 -0.0011
PHE 9LEU 10 0.0002
LEU 10THR 11 -0.0004
THR 11ALA 12 -0.0001
ALA 12ALA 13 -0.0011
ALA 13GLN 14 -0.0001
GLN 14VAL 15 0.0004
VAL 15PHE 16 -0.0000
PHE 16LEU 17 0.0005
LEU 17ALA 18 0.0001
ALA 18PHE 19 -0.0001
PHE 19LEU 20 -0.0002
LEU 20LEU 21 0.0010
LEU 21VAL 22 0.0000
VAL 22LEU 23 -0.0004
LEU 23LEU 24 0.0002
LEU 24VAL 25 -0.0027
VAL 25LEU 26 -0.0001
LEU 26LEU 27 -0.0001
LEU 27GLN 28 -0.0003
GLN 28SER 29 -0.0016
SER 29PRO 30 0.0001
PRO 30GLU 31 0.0005
GLU 31SER 32 -0.0001
SER 32ASP 33 0.0030
ASP 33THR 34 -0.0002
THR 34LEU 35 -0.0003
LEU 35GLY 36 -0.0002
GLY 36GLY 37 -0.0081
GLY 37PHE 38 0.0005
PHE 38GLY 39 0.0003
GLY 39GLY 40 -0.0000
GLY 40PRO 41 0.0053
PRO 41GLN 42 -0.0000
GLN 42CYS 43 0.0001
CYS 43ASN 44 -0.0000
ASN 44LEU 45 -0.0035
LEU 45GLY 46 0.0001
GLY 46SER 47 0.0004
SER 47MET 48 0.0001
MET 48PHE 49 -0.0025
PHE 49GLY 50 0.0002
GLY 50LYS 51 0.0002
LYS 51SER 52 -0.0000
SER 52SER 53 -0.0167
SER 53SER 54 -0.0001
SER 54SER 55 -0.0005
SER 55SER 56 0.0001
SER 56PHE 57 -0.0083
PHE 57ILE 58 -0.0002
ILE 58ALA 59 0.0001
ALA 59LYS 60 0.0002
LYS 60LEU 61 -0.0018
LEU 61THR 62 0.0003
THR 62ALA 63 -0.0001
ALA 63VAL 64 -0.0000
VAL 64VAL 65 -0.0002
VAL 65ALA 66 0.0001
ALA 66ALA 67 0.0001
ALA 67ALA 68 -0.0001
ALA 68PHE 69 -0.0004
PHE 69ILE 70 0.0004
ILE 70VAL 71 -0.0003
VAL 71ASN 72 -0.0004
ASN 72THR 73 -0.0032
THR 73ILE 74 0.0002
ILE 74LEU 75 0.0000
LEU 75LEU 76 -0.0002
LEU 76VAL 77 -0.0057
VAL 77GLY 78 0.0001
GLY 78THR 79 -0.0003
THR 79ASN 80 -0.0002
ASN 80ALA 81 -0.0006
ALA 81ARG 82 -0.0003
ARG 82ARG 83 0.0002
ARG 83VAL 84 -0.0003
VAL 84ARG 85 0.0013
ARG 85GLU 86 -0.0002
GLU 86VAL 87 0.0002
VAL 87SER 88 -0.0002
SER 88VAL 89 -0.0017
VAL 89VAL 90 -0.0002
VAL 90SER 91 -0.0000
SER 91LYS 92 0.0001
LYS 92THR 93 -0.0038
THR 93GLU 94 0.0001
GLU 94ALA 95 -0.0001
ALA 95VAL 96 -0.0002
VAL 96SER 97 -0.0036
SER 97GLY 98 -0.0002
GLY 98GLN 99 -0.0002
GLN 99GLU 100 0.0003
GLU 100SER 101 0.0072
SER 101ASN 102 -0.0000
ASN 102GLY 103 0.0004
GLY 103SER 104 -0.0002
SER 104GLU 105 0.0036
GLU 105VAL 106 0.0002
VAL 106PRO 107 0.0003
PRO 107PHE 108 0.0000
PHE 108GLU 109 0.0009

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elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: april 24th, 2026.