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***  HYDROLASE/HYDROLASE INHIBITOR 26-APR-00 1EWM  ***

CA distance fluctuations for 2610021246531795849

---  normal mode 11  ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok
largest increasereflargest decrease
VAL 210 0.55 ALA 1 -0.51 GLU 184
VAL 210 0.48 PRO 2 -0.39 GLU 184
GLY 212 0.47 ALA 3 -0.41 GLY 146
VAL 5 0.66 ALA 4 -0.56 GLY 146
ALA 4 0.66 VAL 5 -0.56 GLU 184
ASN 167 0.81 ASP 6 -0.71 GLU 184
ASN 167 0.72 TRP 7 -0.62 GLU 184
ALA 167 0.69 ARG 8 -0.84 GLU 184
ALA 167 0.90 ALA 9 -0.89 GLU 184
ALA 167 0.65 ARG 10 -0.67 GLU 184
ALA 167 0.66 GLY 11 -0.60 THR 179
ALA 167 0.57 ALA 12 -0.50 THR 179
ALA 167 0.58 VAL 13 -0.49 THR 179
ALA 167 0.53 THR 14 -0.50 ALA 15
ALA 167 0.49 ALA 15 -0.50 THR 14
ALA 167 0.37 VAL 16 -0.45 ALA 9
ALA 167 0.32 LYS 17 -0.30 ALA 9
GLU 184 0.30 ASP 18 -0.28 ALA 9
TRP 177 0.32 GLN 19 -0.20 ALA 9
GLN 180 0.44 GLY 20 -0.20 ALA 9
GLN 180 0.51 GLN 21 -0.15 ALA 9
TRP 177 0.42 CYS 22 -0.13 SER 24
MET 142 0.51 GLY 23 -0.12 GLN 21
TRP 177 0.37 SER 24 -0.13 CYS 22
ILE 187 0.42 CYS 25 -0.11 GLN 21
GLY 160 0.51 TRP 26 -0.13 LEU 67
ASN 167 0.35 ALA 27 -0.13 ASN 69
ILE 187 0.38 PHE 28 -0.15 ASN 69
ILE 172 0.39 SER 29 -0.17 GLU 112
ASN 167 0.41 ALA 30 -0.16 ASN 69
ASN 167 0.45 ILE 31 -0.17 ASN 69
ASN 167 0.51 GLY 32 -0.21 LYS 17
GLY 165 0.55 ASN 33 -0.24 THR 179
ASN 167 0.48 VAL 34 -0.22 VAL 111
ASN 167 0.48 GLU 35 -0.24 THR 179
ASN 167 0.56 CYS 36 -0.34 THR 179
ASN 167 0.52 GLN 37 -0.27 THR 179
ASN 167 0.48 TRP 38 -0.24 THR 179
ASN 167 0.48 PHE 39 -0.33 THR 179
ALA 4 0.50 LEU 40 -0.34 THR 179
ALA 4 0.48 ALA 41 -0.28 VAL 111
ALA 4 0.45 GLY 42 -0.27 THR 179
ALA 167 0.46 HIS 43 -0.24 THR 179
ALA 167 0.50 PRO 44 -0.26 THR 179
ALA 167 0.52 LEU 45 -0.31 THR 179
ALA 167 0.47 THR 46 -0.22 THR 179
ALA 167 0.45 ASN 47 -0.17 VAL 111
ALA 167 0.42 LEU 48 -0.16 ALA 71
ALA 167 0.37 SER 49 -0.14 GLY 62
ASN 167 0.37 GLU 50 -0.17 GLY 62
ASN 167 0.32 GLN 51 -0.14 GLY 62
ASN 167 0.37 MET 52 -0.12 GLY 62
ASN 167 0.36 LEU 53 -0.14 LEU 48
ASP 158 0.36 VAL 54 -0.23 GLY 62
ASP 158 0.36 SER 55 -0.10 SER 64
ASP 158 0.37 CYS 56 -0.11 TYR 81
ASP 158 0.39 ASP 57 -0.14 SER 61
ASP 158 0.44 LYS 58 -0.13 GLU 78
ASP 158 0.45 THR 59 -0.18 GLN 77
ASP 158 0.55 ASP 60 -0.12 LEU 48
ASP 158 0.65 SER 61 -0.14 SER 64
ASP 158 0.50 GLY 62 -0.23 VAL 54
ASP 158 0.49 CYS 63 -0.12 VAL 54
ASP 158 0.78 SER 64 -0.14 SER 61
ASP 158 0.89 GLY 65 -0.10 CYS 22
ASP 158 0.74 GLY 66 -0.10 THR 108
ALA 133 0.58 LEU 67 -0.13 TRP 26
ALA 133 0.43 MET 68 -0.14 PHE 28
GLU 205 0.38 ASN 69 -0.17 ILE 31
LEU 157 0.38 ASN 70 -0.18 THR 108
ASN 167 0.37 ALA 71 -0.16 LEU 48
GLY 165 0.40 PHE 72 -0.18 ILE 107
VAL 126 0.44 GLU 73 -0.18 THR 108
THR 97 0.38 TRP 74 -0.15 ILE 75
ASN 127 0.43 ILE 75 -0.15 TRP 74
ASN 127 0.50 VAL 76 -0.13 THR 59
VAL 126 0.47 GLN 77 -0.18 THR 59
THR 97 0.43 GLU 78 -0.13 LYS 58
SER 98 0.50 ASN 78 -0.10 LYS 58
SER 98 0.47 ASN 78 -0.09 THR 59
ASN 127 0.50 GLY 78 -0.12 THR 59
ASN 167 0.43 ALA 79 -0.11 ASP 57
ASN 167 0.44 VAL 80 -0.13 ASP 57
ASN 167 0.42 TYR 81 -0.12 ASP 57
ALA 167 0.40 THR 82 -0.11 GLY 62
ALA 167 0.37 GLU 83 -0.11 PRO 44
ALA 167 0.34 ASP 84 -0.14 PRO 44
ALA 167 0.33 SER 85 -0.13 GLY 99
ALA 167 0.32 TYR 86 -0.08 PRO 44
ALA 167 0.30 PRO 87 -0.13 ALA 89
ALA 167 0.27 TYR 88 -0.15 ALA 89
ALA 167 0.23 ALA 89 -0.15 ALA 9
TRP 177 0.25 SER 89 -0.12 ALA 9
GLN 180 0.29 GLY 89 -0.19 ALA 9
GLN 180 0.29 GLU 89 -0.18 ALA 9
GLN 180 0.36 GLY 90 -0.12 ALA 9
MET 142 0.30 ILE 91 -0.09 THR 46
ASP 158 0.32 SER 92 -0.08 THR 46
ASP 158 0.29 PRO 93 -0.10 SER 98
ASP 158 0.32 PRO 94 -0.07 THR 96
ASP 158 0.31 CYS 95 -0.07 SER 64
ASN 167 0.31 THR 96 -0.10 PRO 93
ASN 78 0.48 THR 97 -0.12 HIS 100
ASN 78 0.50 SER 98 -0.22 GLY 99
ALA 167 0.30 GLY 99 -0.22 SER 98
ALA 167 0.34 HIS 100 -0.12 THR 97
ALA 167 0.37 THR 101 -0.10 THR 97
ASN 167 0.40 VAL 102 -0.10 SER 61
ALA 167 0.42 GLY 103 -0.11 GLU 73
ASN 167 0.45 ALA 105 -0.13 GLU 73
ASN 167 0.45 THR 106 -0.16 GLU 73
ASN 127 0.54 ILE 107 -0.18 PHE 72
ASN 127 0.60 THR 108 -0.18 GLU 73
ASN 127 0.58 GLY 109 -0.15 ASN 70
ASN 127 0.59 HIS 110 -0.20 VAL 210
GLU 73 0.44 VAL 111 -0.28 ALA 41
GLU 73 0.38 GLU 112 -0.24 SER 207
GLU 73 0.36 LEU 113 -0.27 ALA 41
GLU 73 0.29 PRO 114 -0.22 ALA 41
GLU 156 0.29 GLN 115 -0.23 VAL 168
ASN 69 0.25 ASP 116 -0.26 VAL 168
ASN 69 0.29 GLU 117 -0.23 VAL 168
PRO 2 0.28 ALA 118 -0.22 VAL 168
GLU 73 0.31 GLN 119 -0.23 GLU 184
ASN 69 0.36 ILE 120 -0.26 GLU 184
HIS 110 0.40 ALA 121 -0.31 GLU 184
HIS 110 0.47 ALA 122 -0.32 GLU 184
HIS 110 0.48 TRP 123 -0.31 GLU 184
VAL 210 0.50 LEU 124 -0.39 GLU 184
VAL 210 0.58 ALA 125 -0.47 GLU 184
VAL 210 0.71 VAL 126 -0.43 GLU 184
VAL 210 0.82 ASN 127 -0.37 THR 179
VAL 210 0.58 GLY 128 -0.45 THR 179
GLY 165 0.64 PRO 129 -0.40 THR 179
GLY 165 0.44 VAL 130 -0.30 THR 179
ASN 167 0.39 ALA 131 -0.24 VAL 16
LEU 67 0.38 VAL 132 -0.19 VAL 16
LEU 67 0.58 ALA 133 -0.15 VAL 16
GLY 65 0.53 VAL 134 -0.17 LYS 174
GLY 65 0.58 ASP 135 -0.23 VAL 168
SER 64 0.61 ALA 136 -0.20 ARG 8
SER 64 0.63 SER 139 -0.21 VAL 168
SER 64 0.54 SER 140 -0.26 ALA 4
SER 64 0.56 TRP 141 -0.28 ALA 4
SER 64 0.58 MET 142 -0.31 ALA 9
SER 64 0.49 THR 143 -0.30 ALA 4
SER 64 0.46 TYR 144 -0.37 ALA 4
SER 64 0.41 THR 145 -0.44 ALA 4
SER 64 0.37 GLY 146 -0.56 ALA 4
SER 64 0.34 GLY 147 -0.55 ALA 4
SER 64 0.33 VAL 148 -0.43 ALA 4
SER 64 0.37 MET 149 -0.34 ALA 4
SER 64 0.33 THR 151 -0.42 ALA 167
SER 64 0.33 SER 152 -0.39 VAL 168
SER 64 0.40 CYS 153 -0.41 VAL 168
SER 64 0.41 VAL 154 -0.36 VAL 168
SER 64 0.43 SER 155 -0.44 VAL 168
SER 64 0.43 GLU 156 -0.38 VAL 168
SER 64 0.49 GLN 156 -0.29 VAL 168
GLY 66 0.61 LEU 157 -0.22 VAL 168
GLY 65 0.89 ASP 158 -0.15 VAL 168
GLY 65 0.74 HIS 159 -0.11 ASP 18
TRP 26 0.51 GLY 160 -0.13 ASP 18
TRP 26 0.44 VAL 161 -0.19 SER 176
ILE 172 0.45 LEU 162 -0.25 THR 179
ASN 167 0.39 LEU 163 -0.30 THR 179
ASN 167 0.53 VAL 164 -0.42 GLU 184
PRO 129 0.64 GLY 165 -0.49 GLU 184
ASN 167 0.62 TYR 166 -0.39 ARG 188
ASP 6 0.81 ASN 167 -0.42 GLY 147
ALA 9 0.63 ASP 167 -0.22 CYS 153
ALA 9 0.89 SER 167 -0.26 CYS 153
ALA 9 0.90 ALA 167 -0.42 THR 151
ALA 9 0.71 ALA 167 -0.41 THR 151
ALA 9 0.57 VAL 168 -0.53 SER 193
ALA 9 0.49 PRO 169 -0.31 CYS 153
GLY 32 0.37 TYR 170 -0.32 CYS 153
GLY 32 0.34 TRP 171 -0.23 ARG 188
GLY 32 0.47 ILE 172 -0.39 ILE 187
TRP 26 0.33 ILE 173 -0.25 ALA 125
PHE 28 0.35 LYS 174 -0.31 THR 179
ILE 187 0.40 ASN 175 -0.27 ALA 9
ILE 187 0.28 SER 176 -0.27 ALA 9
GLY 23 0.47 TRP 177 -0.38 ALA 9
GLY 20 0.38 THR 178 -0.52 ALA 9
GLN 21 0.36 THR 179 -0.82 ALA 9
GLN 21 0.51 GLN 180 -0.74 ALA 9
GLY 23 0.43 TRP 181 -0.54 ALA 9
SER 64 0.38 GLY 182 -0.51 ALA 9
GLY 23 0.36 GLU 183 -0.63 ASP 6
GLN 21 0.33 GLU 184 -0.89 ALA 9
VAL 16 0.31 GLY 185 -0.49 ALA 9
ALA 167 0.32 TYR 186 -0.45 ARG 8
CYS 25 0.42 ILE 187 -0.39 ILE 172
GLY 65 0.34 ARG 188 -0.43 ALA 4
GLY 65 0.35 ILE 189 -0.33 CYS 153
GLY 65 0.28 ALA 190 -0.36 CYS 153
GLY 65 0.25 LYS 191 -0.29 ASN 198
SER 64 0.24 GLY 192 -0.39 VAL 168
SER 64 0.27 SER 193 -0.53 VAL 168
GLY 65 0.30 ASN 198 -0.42 VAL 168
GLY 65 0.35 GLN 199 -0.40 VAL 168
GLY 65 0.43 CYS 200 -0.30 VAL 168
GLY 65 0.38 LEU 201 -0.31 VAL 168
GLY 66 0.37 VAL 202 -0.18 VAL 168
GLY 66 0.31 LYS 203 -0.21 VAL 168
GLU 156 0.31 GLU 204 -0.20 VAL 168
ASN 69 0.38 GLU 205 -0.18 VAL 16
ASN 69 0.36 ALA 206 -0.21 VAL 16
ALA 122 0.39 SER 207 -0.24 GLU 112
LEU 124 0.43 SER 208 -0.23 VAL 111
ASN 127 0.49 ALA 209 -0.24 VAL 111
ASN 127 0.82 VAL 210 -0.26 VAL 111
ASN 127 0.62 VAL 211 -0.17 THR 179
VAL 126 0.63 GLY 212 -0.13 THR 179

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elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: april 24th, 2026.