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* gluc-protot-model1 *

CA distance fluctuations for 2610071411493079079

--- normal mode 25 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
GLU 162 0.13 GLY 132 -0.26 GLY 786

GLU 162 0.14 ASN 133 -0.22 GLY 786

GLU 162 0.16 TYR 134 -0.23 GLU 934

SER 155 0.17 ASP 135 -0.24 ILE 1058

SER 155 0.21 PRO 136 -0.30 ILE 1058

SER 155 0.23 ASN 137 -0.30 GLU 1057

GLU 741 0.20 ALA 138 -0.25 ILE 1058

ALA 153 0.23 ILE 139 -0.26 HIS 1055

ALA 153 0.30 ALA 140 -0.33 HIS 1055

ALA 140 0.26 MET 141 -0.29 PRO 266

GLU 741 0.25 ALA 142 -0.30 PRO 266

ALA 153 0.21 LEU 143 -0.32 PRO 266

ALA 153 0.26 PRO 144 -0.35 PRO 266

GLY 985 0.20 ASN 145 -0.42 HIS 1055

ILE 161 0.23 GLU 146 -0.39 PRO 266

TYR 901 0.22 PRO 147 -0.41 PRO 266

TYR 901 0.22 TYR 148 -0.44 PRO 266

TYR 901 0.19 PRO 149 -0.42 PRO 266

ASN 838 0.22 ALA 150 -0.47 PRO 266

TYR 901 0.18 TRP 151 -0.52 PRO 266

ALA 140 0.23 THR 152 -0.51 PRO 266

ALA 140 0.30 ALA 153 -0.48 PRO 266

ALA 140 0.26 ASP 154 -0.53 PRO 266

ALA 140 0.27 SER 155 -0.58 PRO 266

ALA 140 0.21 GLN 156 -0.65 PRO 266

ALA 140 0.19 SER 157 -0.66 PRO 266

ALA 140 0.17 PRO 158 -0.76 PRO 266

ALA 140 0.19 VAL 159 -0.71 PRO 266

ALA 140 0.22 SER 160 -0.62 PRO 266

GLU 146 0.23 ILE 161 -0.56 PRO 266

TYR 901 0.22 GLU 162 -0.54 PRO 266

TYR 901 0.21 GLN 163 -0.60 PRO 266

TYR 901 0.21 ILE 164 -0.58 PRO 266

TYR 901 0.23 GLU 165 -0.51 PRO 266

TYR 901 0.22 ASP 166 -0.53 PRO 266

TYR 901 0.21 ILE 167 -0.55 PRO 266

TYR 901 0.24 PHE 168 -0.50 PRO 266

TYR 901 0.25 ILE 169 -0.47 PRO 266

TYR 901 0.23 ASP 170 -0.48 PRO 266

TYR 901 0.22 LEU 171 -0.45 PRO 266

TYR 901 0.24 THR 172 -0.41 PRO 266

TYR 901 0.24 ASN 173 -0.40 PRO 266

TYR 901 0.22 ARG 174 -0.39 PRO 266

TYR 901 0.22 LEU 175 -0.36 PRO 266

TYR 901 0.23 GLY 176 -0.34 PRO 266

TYR 901 0.23 PHE 177 -0.35 PRO 266

TYR 901 0.25 GLN 178 -0.35 PRO 266

TYR 901 0.27 ARG 179 -0.38 PRO 266

TYR 901 0.28 ASP 180 -0.37 PRO 266

TYR 901 0.26 SER 181 -0.37 PRO 266

TYR 901 0.26 MET 182 -0.41 PRO 266

TYR 901 0.28 ARG 183 -0.42 PRO 266

TYR 901 0.28 ASN 184 -0.40 PRO 266

TYR 901 0.25 MET 185 -0.42 PRO 266

TYR 901 0.24 PHE 186 -0.46 PRO 266

TYR 901 0.26 ASP 187 -0.43 PRO 266

TYR 901 0.24 HIS 188 -0.41 PRO 266

TYR 901 0.22 PHE 189 -0.47 PRO 266

TYR 901 0.23 MET 190 -0.49 PRO 266

TYR 901 0.23 VAL 191 -0.43 PRO 266

TYR 901 0.21 LEU 192 -0.44 PRO 266

TYR 901 0.20 LEU 193 -0.51 PRO 266

TYR 901 0.20 ASP 194 -0.47 PRO 266

TYR 901 0.19 SER 195 -0.40 PRO 266

TYR 901 0.17 ARG 196 -0.44 PRO 266

TYR 901 0.17 SER 197 -0.49 PRO 266

ASN 838 0.20 SER 198 -0.42 PRO 266

TYR 901 0.15 ARG 199 -0.40 PRO 266

TYR 901 0.15 MET 200 -0.47 PRO 266

TYR 901 0.15 SER 201 -0.57 PRO 266

TYR 901 0.16 PRO 202 -0.61 PRO 266

TYR 901 0.15 ASP 203 -0.73 PRO 266

TYR 901 0.14 GLN 204 -0.62 PRO 266

TYR 901 0.16 ALA 205 -0.55 PRO 266

TYR 901 0.16 LEU 206 -0.63 PRO 266

TYR 901 0.15 LEU 207 -0.64 PRO 266

TYR 901 0.15 SER 208 -0.49 PRO 266

TYR 901 0.16 LEU 209 -0.47 PRO 266

TYR 901 0.16 HIS 210 -0.51 PRO 266

TYR 901 0.15 ALA 211 -0.42 PRO 266

TYR 901 0.15 ASP 212 -0.34 PRO 266

TYR 901 0.17 TYR 213 -0.36 PRO 266

TYR 901 0.16 ILE 214 -0.37 PRO 266

TYR 901 0.15 GLY 215 -0.37 PRO 266

TYR 901 0.14 GLY 216 -0.28 PRO 266

TYR 901 0.13 ASP 217 -0.16 GLU 283

TYR 901 0.13 THR 218 -0.16 PRO 266

TYR 901 0.15 ALA 219 -0.23 PRO 266

TYR 901 0.15 ASN 220 -0.19 PRO 266

TYR 901 0.16 TYR 221 -0.23 PRO 266

TYR 901 0.15 LYS 222 -0.18 PRO 266

TYR 901 0.14 LYS 223 -0.09 PRO 266

ASN 280 0.19 TRP 224 -0.12 PRO 266

ASN 280 0.23 TYR 225 -0.13 PRO 266

ASN 280 0.26 PHE 226 -0.06 ALA 1823

ASN 280 0.27 ALA 227 -0.06 ALA 1823

ASN 280 0.32 ALA 228 -0.06 ALA 1823

ASN 280 0.37 GLN 229 -0.08 PRO 266

ASN 280 0.51 LEU 230 -0.11 ASP 231

ASN 280 0.42 ASP 231 -0.11 LEU 230

SER 281 0.34 MET 232 -0.06 ALA 1823

ASN 280 0.21 ASP 233 -0.06 ALA 1823

THR 272 0.23 ASP 234 -0.06 ALA 1823

THR 272 0.27 GLU 235 -0.06 ALA 1823

ASP 268 0.20 ILE 236 -0.07 ALA 1823

ASP 268 0.21 GLY 237 -0.07 ALA 1823

ASP 268 0.29 PHE 238 -0.08 PRO 1283

ASP 268 0.28 ARG 239 -0.08 PRO 612

ASP 268 0.22 ASN 240 -0.10 PRO 612

ASP 268 0.27 MET 241 -0.13 PRO 1283

GLY 1136 0.45 PRO 266 -0.96 GLN 295

GLY 1136 0.28 GLU 267 -0.82 GLN 295

TYR 592 0.35 ASP 268 -0.69 GLN 295

GLU 283 0.28 THR 269 -0.81 GLN 295

GLY 1136 0.16 GLU 270 -0.65 GLN 295

LYS 275 0.26 GLU 271 -0.47 GLN 295

ILE 276 0.37 THR 272 -0.47 PRO 1135

GLU 416 0.22 LEU 273 -0.23 PRO 1135

GLU 416 0.25 ASN 274 -0.20 GLU 277

GLU 416 0.30 LYS 275 -0.39 GLY 1136

THR 272 0.37 ILE 276 -0.35 GLY 1136

GLU 416 0.39 GLU 277 -0.24 GLY 1136

GLU 416 0.43 GLY 278 -0.17 GLY 1136

GLU 416 0.35 ASP 279 -0.20 GLY 1136

LEU 230 0.51 ASN 280 -0.12 ALA 284

MET 232 0.34 SER 281 -0.12 TYR 1139

THR 272 0.25 LEU 282 -0.06 HIS 614

THR 272 0.32 GLU 283 -0.26 TYR 1139

THR 272 0.35 ALA 284 -0.14 ASP 279

LEU 230 0.20 ALA 285 -0.09 TYR 1139

ILE 415 0.15 ASP 286 -0.12 GLU 283

GLU 416 0.15 PHE 287 -0.17 ILE 276

GLU 416 0.17 ARG 288 -0.17 GLU 270

ILE 415 0.15 TRP 289 -0.22 PRO 266

PRO 418 0.12 LYS 290 -0.26 THR 269

PRO 418 0.14 ALA 291 -0.52 THR 269

PRO 418 0.14 LYS 292 -0.50 PRO 266

TYR 901 0.13 MET 293 -0.57 PRO 266

TYR 901 0.12 ASN 294 -0.76 PRO 266

PRO 418 0.13 GLN 295 -0.96 PRO 266

TYR 901 0.14 LEU 296 -0.88 PRO 266

TYR 901 0.15 SER 297 -0.96 PRO 266

TYR 901 0.16 PRO 298 -0.84 PRO 266

TYR 901 0.18 LEU 299 -0.74 PRO 266

TYR 901 0.17 GLU 300 -0.70 PRO 266

TYR 901 0.17 ARG 301 -0.66 PRO 266

TYR 901 0.19 VAL 302 -0.63 PRO 266

TYR 901 0.20 ARG 303 -0.58 PRO 266

TYR 901 0.19 HIS 304 -0.52 PRO 266

TYR 901 0.19 ILE 305 -0.50 PRO 266

TYR 901 0.21 ALA 306 -0.48 PRO 266

TYR 901 0.21 LEU 307 -0.43 PRO 266

TYR 901 0.20 TYR 308 -0.39 PRO 266

TYR 901 0.21 LEU 309 -0.39 PRO 266

TYR 901 0.23 LEU 310 -0.38 PRO 266

TYR 901 0.21 CYS 311 -0.34 PRO 266

TYR 901 0.21 TRP 312 -0.32 PRO 266

TYR 901 0.23 GLY 313 -0.33 PRO 266

TYR 901 0.23 GLU 314 -0.31 PRO 266

TYR 901 0.21 ALA 315 -0.26 PRO 266

TYR 901 0.21 ASN 316 -0.24 PRO 266

TYR 901 0.19 GLN 317 -0.20 PRO 266

TYR 901 0.19 VAL 318 -0.20 PRO 266

TYR 901 0.19 ARG 319 -0.22 PRO 266

TYR 901 0.18 PHE 320 -0.18 PRO 266

TYR 901 0.17 THR 321 -0.16 PRO 266

TYR 901 0.17 ALA 322 -0.19 PRO 266

ASN 280 0.18 GLU 323 -0.16 PRO 266

ASN 280 0.19 CYS 324 -0.18 PRO 266

TYR 901 0.18 LEU 325 -0.23 PRO 266

TYR 901 0.18 CYS 326 -0.23 PRO 266

GLY 278 0.21 PHE 327 -0.20 PRO 266

TYR 901 0.18 ILE 328 -0.25 PRO 266

TYR 901 0.19 TYR 329 -0.30 PRO 266

GLY 278 0.19 LYS 330 -0.26 PRO 266

GLY 278 0.21 CYS 331 -0.25 PRO 266

TYR 901 0.19 ALA 332 -0.31 PRO 266

TYR 901 0.19 LEU 333 -0.36 PRO 266

TYR 901 0.18 ASP 334 -0.30 PRO 266

TYR 901 0.19 TYR 335 -0.31 PRO 266

TYR 901 0.20 LEU 336 -0.38 PRO 266

TYR 901 0.19 ASP 337 -0.40 PRO 266

TYR 901 0.19 SER 338 -0.32 PRO 266

TYR 901 0.19 PRO 339 -0.31 PRO 266

TYR 901 0.19 LEU 340 -0.29 PRO 266

TYR 901 0.20 CYS 341 -0.34 PRO 266

TYR 901 0.21 GLN 342 -0.38 PRO 266

TYR 901 0.20 GLN 343 -0.33 PRO 266

TYR 901 0.21 ARG 344 -0.32 PRO 266

TYR 901 0.22 GLN 345 -0.35 PRO 266

TYR 901 0.23 GLU 346 -0.33 PRO 266

TYR 901 0.23 PRO 347 -0.36 PRO 266

TYR 901 0.22 MET 348 -0.33 PRO 266

TYR 901 0.23 PRO 349 -0.31 PRO 266

TYR 901 0.24 GLU 350 -0.32 PRO 266

TYR 901 0.23 GLY 351 -0.30 PRO 266

TYR 901 0.22 ASP 352 -0.28 PRO 266

TYR 901 0.21 PHE 353 -0.29 PRO 266

TYR 901 0.21 LEU 354 -0.27 PRO 266

TYR 901 0.21 ASN 355 -0.24 PRO 266

TYR 901 0.20 ARG 356 -0.23 PRO 266

TYR 901 0.20 VAL 357 -0.23 PRO 266

TYR 901 0.20 ILE 358 -0.23 PRO 266

TYR 901 0.20 THR 359 -0.22 PRO 266

TYR 901 0.18 PRO 360 -0.18 PRO 266

GLY 278 0.18 ILE 361 -0.17 PRO 266

TYR 901 0.19 TYR 362 -0.18 PRO 266

TYR 901 0.18 HIS 363 -0.16 PRO 266

GLY 278 0.18 PHE 364 -0.14 PRO 266

TYR 901 0.17 ILE 365 -0.15 PRO 266

TYR 901 0.17 ARG 366 -0.15 PRO 266

TYR 901 0.16 ASN 367 -0.13 PRO 266

GLY 278 0.16 GLN 368 -0.13 ARG 1538

TYR 901 0.15 VAL 369 -0.13 ASP 1551

TYR 901 0.16 TYR 370 -0.14 ARG 1538

TYR 901 0.15 GLU 371 -0.17 ARG 1538

TYR 901 0.15 ILE 372 -0.16 LEU 1540

TYR 901 0.14 VAL 373 -0.20 LEU 1540

TYR 901 0.14 ASP 374 -0.21 LEU 1540

TYR 901 0.15 GLY 375 -0.16 GLY 1542

TYR 901 0.15 ARG 376 -0.16 LEU 1540

TYR 901 0.16 PHE 377 -0.15 PRO 266

TYR 901 0.15 VAL 378 -0.15 LEU 1540

TYR 901 0.15 LYS 379 -0.13 ASP 1551

TYR 901 0.14 ARG 380 -0.15 ARG 1538

TYR 901 0.14 GLU 381 -0.14 PHE 1536

TYR 901 0.14 ARG 382 -0.14 ASP 432

TYR 901 0.14 ASP 383 -0.13 SER 1553

TYR 901 0.14 HIS 384 -0.12 ASP 432

TYR 901 0.14 ASN 385 -0.13 PHE 436

GLY 278 0.14 LYS 386 -0.17 ASP 432

TYR 901 0.15 ILE 387 -0.17 ASP 432

TYR 901 0.15 VAL 388 -0.16 ASP 432

TYR 901 0.16 GLY 389 -0.10 PRO 266

TYR 901 0.17 TYR 390 -0.13 PRO 266

TYR 901 0.16 ASP 391 -0.10 PRO 266

ASN 280 0.17 ASP 392 -0.08 PRO 266

ASN 280 0.18 LEU 393 -0.11 PRO 266

ASN 280 0.18 ASN 394 -0.11 PRO 266

ASN 280 0.20 GLN 395 -0.07 PRO 266

ASN 280 0.23 LEU 396 -0.08 LEU 419

ASN 280 0.25 PHE 397 -0.10 PRO 266

ASN 280 0.25 TRP 398 -0.06 ALA 1812

ASN 280 0.31 TYR 399 -0.08 LEU 419

ASN 280 0.39 PRO 400 -0.10 LEU 419

ASN 280 0.36 GLU 401 -0.09 LEU 419

ASN 280 0.30 GLY 402 -0.10 THR 438

GLY 278 0.33 ILE 403 -0.10 LEU 419

GLY 278 0.38 ALA 404 -0.15 ILE 415

GLY 278 0.32 LYS 405 -0.13 LYS 437

GLY 278 0.31 ILE 406 -0.13 LYS 437

GLY 278 0.30 VAL 407 -0.13 LYS 437

GLY 278 0.29 LEU 408 -0.12 MET 1721

GLY 278 0.26 GLU 409 -0.14 MET 1721

GLY 278 0.28 ASP 410 -0.14 MET 1721

GLY 278 0.31 GLY 411 -0.14 ARG 1557

GLY 278 0.34 THR 412 -0.12 ARG 1557

GLY 278 0.37 LYS 413 -0.12 LYS 437

GLY 278 0.35 LEU 414 -0.12 LYS 437

GLY 278 0.42 ILE 415 -0.15 ALA 404

GLY 278 0.43 GLU 416 -0.11 LYS 521

GLY 278 0.37 LEU 417 -0.10 MET 1721

GLY 278 0.36 PRO 418 -0.11 PRO 266

GLY 278 0.31 LEU 419 -0.15 PRO 266

GLY 278 0.23 GLU 420 -0.22 PRO 266

GLY 278 0.25 GLU 421 -0.19 PRO 266

GLY 278 0.27 ARG 422 -0.17 PRO 266

GLY 278 0.22 TYR 423 -0.23 PRO 266

GLY 278 0.20 LEU 424 -0.23 PRO 266

GLY 278 0.24 ARG 425 -0.18 PRO 266

GLY 278 0.24 LEU 426 -0.18 PRO 266

GLY 278 0.21 GLY 427 -0.19 PRO 266

GLY 278 0.25 ASP 428 -0.15 PRO 266

GLY 278 0.26 VAL 429 -0.13 PRO 266

GLY 278 0.24 VAL 430 -0.13 MET 1721

GLY 278 0.23 TRP 431 -0.13 VAL 388

GLY 278 0.22 ASP 432 -0.17 LYS 386

GLY 278 0.24 ASP 433 -0.15 LYS 386

GLY 278 0.26 VAL 434 -0.14 LYS 437

GLY 278 0.22 PHE 435 -0.20 LYS 437

GLY 278 0.21 PHE 436 -0.41 LYS 437

ASN 280 0.17 LYS 437 -0.41 PHE 436

ASN 280 0.17 THR 438 -0.17 PHE 436

ASN 280 0.15 TYR 439 -0.15 PHE 436

TYR 901 0.14 LYS 440 -0.16 PHE 436

TYR 901 0.14 GLU 441 -0.12 PHE 436

TYR 901 0.13 THR 442 -0.11 HIS 1556

TYR 901 0.13 ARG 443 -0.13 LEU 1417

TYR 901 0.12 THR 444 -0.11 SER 1456

TYR 901 0.12 TRP 445 -0.13 LEU 1306

TYR 901 0.12 LEU 446 -0.11 LEU 1306

TYR 901 0.13 HIS 447 -0.09 SER 1456

TYR 901 0.12 LEU 448 -0.10 PHE 1303

TYR 901 0.12 VAL 449 -0.10 LEU 1306

TYR 901 0.12 THR 450 -0.09 ALA 1823

TYR 901 0.13 ASN 451 -0.09 ALA 1823

TYR 901 0.12 PHE 452 -0.09 ALA 1823

ASP 268 0.12 ASN 453 -0.09 ALA 1823

ASP 268 0.13 ARG 454 -0.10 ALA 1823

TYR 901 0.11 ILE 455 -0.10 ALA 1823

TYR 901 0.11 TRP 456 -0.10 ALA 1823

ASP 268 0.13 VAL 457 -0.10 ALA 1823

ASP 268 0.12 MET 458 -0.10 ALA 1823

ASP 268 0.11 HIS 459 -0.11 ALA 1823

ASP 268 0.12 ILE 460 -0.11 ALA 1823

GLY 499 0.14 SER 461 -0.10 ALA 1823

ASP 268 0.12 ILE 462 -0.11 ALA 1823

ASP 268 0.11 PHE 463 -0.11 ALA 1823

ASP 268 0.13 TRP 464 -0.11 ALA 1823

ASP 268 0.13 MET 465 -0.10 ALA 1823

ASP 268 0.12 TYR 466 -0.11 ALA 1823

ASP 268 0.12 PHE 467 -0.11 ALA 1823

ASP 268 0.13 ALA 468 -0.10 ALA 1823

ASP 268 0.13 TYR 469 -0.10 ALA 1823

ASP 268 0.11 ASN 470 -0.11 ALA 1823

ASP 268 0.11 SER 471 -0.11 ALA 1823

ASP 268 0.12 PRO 472 -0.09 ALA 1823

ASP 268 0.12 THR 473 -0.09 ALA 1823

ASP 268 0.13 PHE 474 -0.08 ALA 1823

ASP 268 0.14 TYR 475 -0.07 ALA 1823

ASP 268 0.13 THR 476 -0.07 ALA 1823

ASP 268 0.13 HIS 477 -0.05 ALA 1823

ASP 268 0.12 ASN 478 -0.05 ALA 1823

ASP 268 0.12 TYR 479 -0.07 ALA 1823

ASP 268 0.11 GLN 480 -0.07 ALA 1823

ASP 268 0.10 GLN 481 -0.09 ALA 1823

ASP 268 0.10 LEU 482 -0.08 ALA 1823

ASP 268 0.10 VAL 483 -0.07 ALA 1823

ASP 268 0.11 ASP 484 -0.08 ALA 1823

ASP 268 0.12 ASN 485 -0.07 ALA 1823

ASP 268 0.12 GLN 486 -0.08 ALA 1823

ASP 268 0.13 PRO 487 -0.07 ALA 1823

ASP 268 0.14 LEU 488 -0.07 ALA 1823

ASP 268 0.15 ALA 489 -0.08 ALA 1823

ASP 268 0.16 ALA 490 -0.07 ALA 1823

ASP 268 0.15 TYR 491 -0.07 ALA 1823

ASP 268 0.14 LYS 492 -0.08 ALA 1823

ASP 268 0.15 TRP 493 -0.08 ALA 1823

ASP 268 0.16 ALA 494 -0.08 ALA 1823

ASP 268 0.15 SER 495 -0.09 ALA 1823

ASP 268 0.15 CYS 496 -0.09 ALA 1823

ASP 268 0.17 ALA 497 -0.09 ALA 1823

ASP 268 0.17 LEU 498 -0.09 ALA 1823

ASP 268 0.16 GLY 499 -0.10 ALA 1823

ASP 268 0.18 GLY 500 -0.10 ALA 1823

ASP 268 0.18 THR 501 -0.10 GLY 678

ASP 268 0.16 VAL 502 -0.12 GLY 678

ASP 268 0.17 ALA 503 -0.10 ALA 1823

ASP 268 0.18 SER 504 -0.09 ALA 1823

ASP 268 0.17 LEU 505 -0.11 GLY 678

ASP 268 0.16 ILE 506 -0.12 MET 1310

ASP 268 0.17 GLN 507 -0.10 MET 1310

ASP 268 0.18 ILE 508 -0.11 MET 1310

ASP 268 0.15 VAL 509 -0.12 MET 1310

ASP 268 0.15 ALA 510 -0.11 MET 1310

ASP 268 0.16 THR 511 -0.10 MET 1310

THR 272 0.16 LEU 512 -0.12 MET 1562

THR 272 0.14 CYS 513 -0.12 MET 1562

THR 272 0.14 GLU 514 -0.09 MET 1562

THR 272 0.16 TRP 515 -0.10 MET 1562

THR 272 0.14 SER 516 -0.12 MET 1562

ASN 280 0.14 PHE 517 -0.10 THR 1558

ASN 280 0.16 VAL 518 -0.08 THR 1558

ASN 280 0.18 PRO 519 -0.09 LYS 413

ASP 279 0.19 ARG 520 -0.10 LYS 413

ASP 279 0.22 LYS 521 -0.12 LYS 405

ASN 280 0.23 TRP 522 -0.10 LYS 405

ASN 280 0.25 ALA 523 -0.07 LEU 419

ASN 280 0.20 GLY 524 -0.09 GLY 586

THR 272 0.19 ALA 525 -0.09 GLY 586

THR 272 0.21 GLN 526 -0.16 HIS 527

THR 272 0.23 HIS 527 -0.16 GLN 526

THR 272 0.21 LEU 528 -0.08 MET 1562

THR 272 0.22 SER 529 -0.08 ILE 1566

ASP 268 0.25 ARG 530 -0.08 ALA 1823

ASP 268 0.23 ARG 531 -0.08 ALA 1823

ASP 268 0.21 PHE 532 -0.09 ILE 1570

ASP 268 0.24 TRP 533 -0.09 ILE 1570

ASP 268 0.25 PHE 534 -0.08 ALA 1823

ASP 268 0.23 LEU 535 -0.09 ALA 1823

ASP 268 0.23 CYS 536 -0.10 ILE 1570

ASP 268 0.24 ILE 537 -0.08 ALA 1823

ASP 268 0.23 ILE 538 -0.09 ALA 1823

ASP 268 0.21 PHE 539 -0.10 GLY 678

ASP 268 0.22 GLY 540 -0.09 GLY 678

ASP 268 0.22 ILE 541 -0.08 ALA 1823

ASP 268 0.21 ASN 542 -0.09 ALA 1823

ASP 268 0.20 LEU 543 -0.09 GLY 678

ASP 268 0.20 GLY 544 -0.08 ALA 1823

ASP 268 0.20 PRO 545 -0.07 ALA 1823

ASP 268 0.19 ILE 546 -0.07 ALA 1823

ASP 268 0.19 ILE 547 -0.07 ALA 1823

ASP 268 0.19 PHE 548 -0.06 ALA 1823

ASP 268 0.18 VAL 549 -0.06 ALA 1823

ASP 268 0.17 PHE 550 -0.06 ALA 1823

ASP 268 0.18 ALA 551 -0.05 ALA 1823

ASP 268 0.18 TYR 552 -0.05 ALA 1823

ASP 268 0.17 ASP 553 -0.05 ALA 1823

ASP 268 0.17 LYS 554 -0.04 ALA 1823

ASP 268 0.17 ASP 555 -0.04 ALA 1823

ASP 268 0.17 THR 556 -0.04 ALA 1823

ASP 268 0.18 VAL 557 -0.04 ALA 1823

ASP 268 0.18 TYR 558 -0.04 ALA 1823

ASP 268 0.17 SER 559 -0.05 ALA 1823

ASP 268 0.17 THR 560 -0.05 ALA 1823

ASP 268 0.18 ALA 561 -0.05 ALA 1823

ASP 268 0.18 ALA 562 -0.06 ALA 1823

ASP 268 0.17 HIS 563 -0.06 ALA 1823

ASP 268 0.18 VAL 564 -0.06 ALA 1823

ASP 268 0.19 VAL 565 -0.07 ALA 1823

ASP 268 0.18 ALA 566 -0.07 ALA 1823

ASP 268 0.17 ALA 567 -0.07 ALA 1823

ASP 268 0.19 VAL 568 -0.07 ALA 1823

ASP 268 0.19 MET 569 -0.08 ALA 1823

ASP 268 0.18 PHE 570 -0.08 ALA 1823

ASP 268 0.18 PHE 571 -0.08 ALA 1823

ASP 268 0.20 VAL 572 -0.08 ALA 1823

ASP 268 0.19 ALA 573 -0.09 ALA 1823

ASP 268 0.18 VAL 574 -0.09 ALA 1823

ASP 268 0.20 ALA 575 -0.09 ALA 1823

ASP 268 0.20 THR 576 -0.09 ALA 1823

ASP 268 0.17 ILE 577 -0.10 ALA 1823

ASP 268 0.18 ILE 578 -0.10 ALA 1823

ASP 268 0.20 PHE 579 -0.09 ALA 1823

ASP 268 0.18 PHE 580 -0.09 ALA 1823

ASP 268 0.16 SER 581 -0.10 MET 458

ASP 268 0.17 ILE 582 -0.09 ALA 1823

ASP 268 0.19 MET 583 -0.09 ALA 1823

ASP 268 0.17 PRO 584 -0.09 ALA 1823

ASP 268 0.17 LEU 585 -0.09 ALA 1823

ASP 268 0.18 GLY 586 -0.09 GLY 524

ASP 268 0.22 GLY 587 -0.09 ARG 599

ASP 268 0.23 LEU 588 -0.08 ALA 1823

ASP 268 0.26 PHE 589 -0.09 GLN 526

ASP 268 0.28 THR 590 -0.08 GLN 526

ASP 268 0.32 SER 591 -0.08 ALA 1823

ASP 268 0.35 TYR 592 -0.07 ALA 1823

ASP 268 0.32 MET 593 -0.06 ALA 1823

THR 272 0.28 THR 597 -0.06 ALA 1823

THR 272 0.24 ARG 598 -0.06 ALA 1823

THR 272 0.23 ARG 599 -0.09 GLY 587

THR 272 0.19 TYR 600 -0.07 GLY 587

THR 272 0.17 VAL 601 -0.07 ALA 1823

ASN 280 0.15 ALA 602 -0.07 ALA 1823

ASN 280 0.17 SER 603 -0.07 ALA 1823

THR 272 0.14 GLN 604 -0.07 ALA 1823

TYR 901 0.14 THR 605 -0.07 ALA 1823

TYR 901 0.14 PHE 606 -0.07 ALA 1823

TYR 901 0.14 THR 607 -0.07 ALA 1823

TYR 901 0.13 ALA 608 -0.07 ALA 1823

TYR 901 0.13 ALA 609 -0.07 ALA 1823

TYR 901 0.13 PHE 610 -0.08 ASN 240

TYR 901 0.13 ALA 611 -0.11 GLU 283

TYR 901 0.12 PRO 612 -0.11 GLU 283

VAL 1127 0.11 LEU 613 -0.10 LYS 275

PRO 266 0.14 HIS 614 -0.12 LYS 275

PRO 266 0.16 GLY 615 -0.13 LYS 275

PRO 266 0.13 LEU 616 -0.12 LYS 275

VAL 1127 0.12 ASP 617 -0.10 LYS 275

PRO 266 0.13 ARG 618 -0.10 LYS 275

PRO 266 0.15 TRP 619 -0.09 LYS 275

PRO 266 0.11 MET 620 -0.09 ALA 1823

TYR 901 0.10 SER 621 -0.09 ALA 1823

PRO 266 0.13 TYR 622 -0.10 ALA 1823

PRO 266 0.12 LEU 623 -0.10 ALA 1823

PRO 266 0.09 VAL 624 -0.10 ALA 1823

PRO 266 0.10 TRP 625 -0.10 ALA 1823

PRO 266 0.12 VAL 626 -0.10 ALA 1823

PRO 266 0.11 THR 627 -0.11 ALA 1823

TYR 901 0.09 VAL 628 -0.11 ALA 1823

PRO 266 0.10 PHE 629 -0.11 ALA 1823

PRO 266 0.11 ALA 630 -0.11 ALA 1823

PRO 266 0.10 ALA 631 -0.12 ALA 1823

PRO 266 0.09 LYS 632 -0.12 ALA 1823

PRO 266 0.10 TYR 633 -0.12 ALA 1823

PRO 266 0.10 SER 634 -0.12 ALA 1823

PRO 266 0.09 GLU 635 -0.13 ALA 1823

PRO 266 0.08 SER 636 -0.13 ALA 1823

PRO 266 0.10 TYR 637 -0.13 ALA 1823

PRO 266 0.09 TYR 638 -0.14 ALA 1823

PRO 266 0.08 PHE 639 -0.15 ALA 1823

ASP 268 0.08 LEU 640 -0.14 ALA 1823

ASP 268 0.09 VAL 641 -0.13 ALA 1823

ASP 268 0.09 LEU 642 -0.14 ALA 1823

ASP 268 0.08 SER 643 -0.15 ALA 1823

ASP 268 0.08 LEU 644 -0.14 ALA 1823

ASP 268 0.09 ARG 645 -0.13 ALA 1823

ASP 268 0.09 ASP 646 -0.14 ALA 1823

ASP 268 0.08 PRO 647 -0.14 ALA 1823

ASP 268 0.09 ILE 648 -0.12 ALA 1823

ASP 268 0.10 ARG 649 -0.11 ALA 1823

ASP 268 0.09 ILE 650 -0.12 ALA 1823

LYS 1011 0.09 LEU 651 -0.11 ALA 1823

ASP 268 0.10 SER 652 -0.10 ALA 1823

ASP 268 0.10 THR 653 -0.10 ALA 1823

ASP 268 0.09 THR 654 -0.10 ALA 1823

ASP 268 0.09 ALA 655 -0.09 ALA 1823

CYS 1689 0.09 MET 656 -0.10 ALA 1823

LEU 1693 0.10 ARG 657 -0.09 ALA 1823

CYS 1689 0.11 CYS 658 -0.08 ALA 1823

MET 1694 0.12 THR 659 -0.08 ALA 666

CYS 1689 0.13 GLY 660 -0.07 ALA 1584

CYS 1689 0.16 GLU 661 -0.06 ALA 1584

MET 1694 0.18 TYR 662 -0.04 GLN 1585

LEU 1693 0.22 TRP 663 -0.03 GLN 1585

LEU 1693 0.20 TRP 664 -0.04 ALA 1823

LEU 1693 0.17 GLY 665 -0.07 THR 659

LEU 1693 0.14 ALA 666 -0.08 THR 659

LEU 1693 0.14 VAL 667 -0.06 ALA 1823

ALA 1569 0.14 LEU 668 -0.06 ALA 1823

CYS 1689 0.11 CYS 669 -0.07 ALA 1823

CYS 1689 0.11 LYS 670 -0.08 ALA 1823

LEU 668 0.14 VAL 671 -0.08 ALA 1823

ALA 1569 0.11 GLN 672 -0.10 ALA 1823

LYS 1011 0.09 PRO 673 -0.11 ALA 1823

GLY 678 0.17 LYS 674 -0.10 ALA 1823

GLY 678 0.17 ILE 675 -0.09 ALA 1823

LYS 1011 0.10 VAL 676 -0.12 ALA 1823

VAL 680 0.10 LEU 677 -0.11 ALA 1823

LYS 674 0.17 GLY 678 -0.12 VAL 502

ILE 675 0.14 LEU 679 -0.11 ALA 1823

LEU 677 0.10 VAL 680 -0.13 ALA 1823

TYR 901 0.09 ILE 681 -0.11 ALA 1823

TYR 901 0.10 ALA 682 -0.11 ILE 506

PHE 10 0.11 THR 683 -0.13 ALA 1823

LEU 687 0.11 ASP 684 -0.13 ALA 1823

TYR 901 0.10 PHE 685 -0.12 ALA 1823

TYR 901 0.11 ILE 686 -0.12 ALA 1823

ASP 684 0.11 LEU 687 -0.13 ALA 1823

TYR 901 0.09 PHE 688 -0.12 ALA 1823

TYR 901 0.10 PHE 689 -0.11 ALA 1823

TYR 901 0.10 LEU 690 -0.12 ALA 1823

TYR 901 0.09 ASP 691 -0.13 ALA 1823

TYR 901 0.10 THR 692 -0.12 ALA 1823

TYR 901 0.10 TYR 693 -0.12 ALA 1823

TYR 901 0.09 LEU 694 -0.13 ALA 1823

TYR 901 0.09 TRP 695 -0.12 ALA 1823

TYR 901 0.09 TYR 696 -0.11 ALA 1823

TYR 901 0.09 ILE 697 -0.11 ALA 1823

GLN 917 0.09 ILE 698 -0.12 ALA 1823

LEU 914 0.09 VAL 699 -0.11 ALA 1823

TYR 901 0.09 ASN 700 -0.10 ALA 1823

LEU 914 0.10 THR 701 -0.11 ALA 1823

LEU 914 0.10 ILE 702 -0.11 ALA 1823

LEU 914 0.10 PHE 703 -0.10 ALA 1823

LEU 914 0.10 SER 704 -0.10 ALA 1823

LEU 914 0.11 VAL 705 -0.10 ALA 1823

LEU 914 0.11 GLY 706 -0.10 LYS 275

LEU 914 0.10 LYS 707 -0.10 LYS 275

LEU 914 0.11 SER 708 -0.10 LYS 275

LEU 914 0.12 PHE 709 -0.11 LYS 275

LEU 914 0.12 TYR 710 -0.12 LYS 275

LEU 914 0.12 LEU 711 -0.12 LYS 275

LEU 914 0.13 GLY 712 -0.11 LYS 275

LEU 914 0.13 ILE 713 -0.11 LYS 275

LEU 914 0.13 SER 714 -0.10 LYS 275

LEU 914 0.14 ILE 715 -0.10 LYS 275

LEU 914 0.14 LEU 716 -0.09 LYS 275

LEU 914 0.15 THR 717 -0.10 LYS 275

LEU 914 0.16 PRO 718 -0.10 LYS 275

LEU 914 0.15 TRP 719 -0.11 LYS 275

LEU 914 0.15 ARG 720 -0.11 LYS 275

LEU 914 0.16 ASN 721 -0.11 LYS 275

LEU 914 0.16 ILE 722 -0.11 LYS 275

LEU 914 0.18 PHE 723 -0.11 ALA 983

LEU 914 0.18 THR 724 -0.11 LYS 275

LEU 914 0.16 ARG 725 -0.12 LYS 275

LEU 914 0.16 LEU 726 -0.12 ASP 268

LEU 914 0.16 PRO 727 -0.14 ASP 268

LEU 914 0.15 LYS 728 -0.14 ASP 268

LEU 914 0.14 ARG 729 -0.13 ASP 268

LEU 914 0.14 ILE 730 -0.15 ASP 268

LEU 914 0.14 TYR 731 -0.16 ASP 268

LEU 914 0.13 SER 732 -0.16 ASP 268

LEU 914 0.13 LYS 733 -0.16 ASP 268

LEU 914 0.13 ILE 734 -0.17 ASP 268

TYR 901 0.13 LEU 735 -0.19 ASP 268

ALA 150 0.13 ALA 736 -0.21 ASP 268

ALA 142 0.15 THR 737 -0.21 ASP 268

ALA 142 0.18 THR 738 -0.21 ASP 268

ALA 142 0.21 ASP 739 -0.25 ASP 268

ALA 142 0.23 MET 740 -0.25 ASP 268

ALA 142 0.25 GLU 741 -0.23 ASP 268

ALA 142 0.23 ILE 742 -0.23 ASP 268

ALA 142 0.17 LYS 743 -0.20 ASP 268

LEU 914 0.13 TYR 744 -0.20 ASP 268

LEU 914 0.14 LYS 745 -0.17 ASP 268

LEU 914 0.15 PRO 746 -0.17 ASP 268

LEU 914 0.16 LYS 747 -0.16 ASP 268

LEU 914 0.15 VAL 748 -0.18 ASP 268

LEU 914 0.14 LEU 749 -0.19 ASP 268

LEU 914 0.16 ILE 750 -0.17 ASP 268

LEU 914 0.17 SER 751 -0.16 ASP 268

LEU 914 0.16 GLN 752 -0.19 ALA 983

LEU 914 0.15 VAL 753 -0.17 PRO 266

LEU 914 0.17 TRP 754 -0.17 ALA 983

LEU 914 0.18 ASN 755 -0.22 ALA 983

LEU 914 0.16 ALA 756 -0.23 ALA 983

LEU 914 0.16 ILE 757 -0.19 ALA 983

LEU 914 0.19 ILE 758 -0.20 ALA 983

LEU 914 0.18 ILE 759 -0.24 ALA 983

TYR 901 0.16 SER 760 -0.24 GLU 984

GLN 917 0.17 MET 761 -0.20 GLU 984

GLN 917 0.19 TYR 762 -0.21 GLU 984

GLU 897 0.19 ARG 763 -0.25 GLU 984

TYR 901 0.15 GLU 764 -0.22 GLU 984

GLN 917 0.17 HIS 765 -0.20 GLU 984

GLN 917 0.19 LEU 766 -0.18 GLU 984

GLN 917 0.24 LEU 767 -0.18 GLU 984

GLN 917 0.28 ALA 768 -0.16 GLU 984

LEU 914 0.28 ILE 769 -0.16 GLU 984

LEU 914 0.32 ASP 770 -0.15 ALA 983

LEU 914 0.27 HIS 771 -0.15 ALA 983

LEU 914 0.24 VAL 772 -0.17 ALA 983

LEU 914 0.27 GLN 773 -0.17 ALA 983

LEU 914 0.27 LYS 774 -0.15 ALA 983

LEU 914 0.23 LEU 775 -0.16 ALA 983

LEU 914 0.21 LEU 776 -0.18 ALA 983

LEU 914 0.20 TYR 777 -0.19 ALA 983

LEU 914 0.19 HIS 778 -0.21 ALA 983

LEU 914 0.16 GLN 779 -0.24 GLY 981

LEU 914 0.17 VAL 780 -0.23 GLY 981

LEU 914 0.14 PRO 781 -0.26 GLY 981

LEU 914 0.14 SER 782 -0.24 GLY 981

LEU 914 0.13 GLU 783 -0.22 GLY 981

LEU 914 0.11 ILE 784 -0.23 GLY 981

LEU 914 0.10 GLU 785 -0.26 GLY 981

LEU 914 0.09 GLY 786 -0.30 GLY 981

LEU 914 0.11 LYS 787 -0.28 GLY 981

LEU 914 0.13 ARG 788 -0.28 GLY 981

LEU 914 0.14 THR 789 -0.23 GLY 981

LEU 914 0.16 LEU 790 -0.21 GLY 981

LEU 914 0.18 ARG 791 -0.18 GLY 981

LEU 914 0.20 ALA 792 -0.16 ALA 983

LEU 914 0.22 PRO 793 -0.15 ALA 983

LEU 914 0.24 THR 794 -0.14 ALA 983

LEU 914 0.23 PHE 795 -0.13 ALA 983

LEU 914 0.20 PHE 796 -0.13 ALA 983

LEU 914 0.21 VAL 797 -0.11 ALA 983

LEU 914 0.22 SER 798 -0.11 ALA 983

LEU 914 0.25 PHE 804 -0.10 ALA 983

LEU 914 0.28 GLU 805 -0.10 ALA 983

LEU 914 0.29 THR 806 -0.11 ALA 983

LEU 914 0.28 GLU 807 -0.12 ALA 983

LEU 914 0.26 PHE 808 -0.14 ALA 983

GLN 917 0.24 PHE 809 -0.14 ALA 983

GLN 917 0.25 PRO 810 -0.14 GLU 984

GLN 917 0.23 ARG 811 -0.13 GLU 984

GLN 917 0.19 ASP 812 -0.13 GLU 984

GLN 917 0.19 SER 813 -0.14 GLU 984

GLN 917 0.17 GLU 814 -0.15 GLU 984

GLN 917 0.19 ALA 815 -0.15 GLU 984

GLN 917 0.19 GLU 816 -0.14 GLU 984

GLN 917 0.16 ARG 817 -0.13 GLU 984

GLN 917 0.15 ARG 818 -0.14 GLU 984

LEU 914 0.17 ILE 819 -0.13 ALA 983

LEU 914 0.16 SER 820 -0.12 ALA 983

LEU 914 0.14 PHE 821 -0.11 ALA 983

LEU 914 0.15 PHE 822 -0.12 ASP 268

LEU 914 0.16 ALA 823 -0.11 ASP 268

LEU 914 0.14 GLN 824 -0.11 LYS 275

LEU 914 0.13 SER 825 -0.11 LYS 275

LEU 914 0.14 LEU 826 -0.12 ASP 268

LEU 914 0.14 SER 827 -0.12 LYS 275

LEU 914 0.12 THR 828 -0.12 LYS 275

LEU 914 0.12 PRO 829 -0.14 LYS 275

LEU 914 0.11 ILE 830 -0.14 LYS 275

TYR 901 0.12 PRO 831 -0.16 ASP 268

TYR 901 0.12 GLU 832 -0.18 ASP 268

TYR 901 0.14 PRO 833 -0.21 ASP 268

TYR 901 0.15 LEU 834 -0.25 PRO 266

TYR 901 0.16 PRO 835 -0.27 PRO 266

TYR 901 0.18 VAL 836 -0.29 PRO 266

TYR 901 0.19 ASP 837 -0.34 PRO 266

ALA 150 0.22 ASN 838 -0.34 PRO 266

TYR 901 0.18 MET 839 -0.31 PRO 266

TYR 901 0.20 PRO 840 -0.34 PRO 266

TYR 901 0.22 THR 841 -0.35 PRO 266

TYR 901 0.22 PHE 842 -0.30 PRO 266

TYR 901 0.23 THR 843 -0.29 PRO 266

TYR 901 0.23 VAL 844 -0.25 PRO 266

TYR 901 0.23 LEU 845 -0.24 PRO 266

TYR 901 0.23 THR 846 -0.22 PRO 266

TYR 901 0.22 PRO 847 -0.21 PRO 266

TYR 901 0.23 HIS 848 -0.20 PRO 266

TYR 901 0.21 TYR 849 -0.19 PRO 266

SER 1426 0.26 ALA 850 -0.18 PRO 266

SER 1426 0.24 GLU 851 -0.18 PRO 266

TYR 901 0.20 ARG 852 -0.18 PRO 266

TYR 901 0.25 ILE 853 -0.20 PRO 266

TYR 901 0.24 LEU 854 -0.20 PRO 266

TYR 901 0.18 LEU 855 -0.18 GLU 984

SER 1786 0.19 SER 856 -0.18 GLU 984

ARG 858 0.31 LEU 857 -0.19 GLU 984

LEU 857 0.31 ARG 858 -0.16 PRO 266

LEU 857 0.22 GLU 859 -0.16 PRO 266

SER 1786 0.15 ILE 860 -0.16 GLU 984

THR 936 0.17 ILE 861 -0.16 PRO 922

SER 1786 0.20 ARG 862 -0.14 PRO 266

SER 1786 0.19 GLU 863 -0.14 PRO 266

SER 1786 0.22 ASP 864 -0.15 PRO 266

GLN 1789 0.24 ASP 865 -0.14 PRO 266

GLN 1789 0.27 GLN 866 -0.13 PRO 266

ASP 1498 0.17 PHE 867 -0.13 GLU 1544

GLU 863 0.15 SER 868 -0.12 PRO 266

ALA 932 0.12 ARG 869 -0.12 PRO 266

THR 936 0.12 VAL 870 -0.12 GLU 984

THR 936 0.14 THR 871 -0.13 PRO 266

ARG 940 0.13 LEU 872 -0.14 GLU 984

THR 939 0.13 LEU 873 -0.15 GLU 984

ILE 926 0.12 GLU 874 -0.15 GLU 984

TYR 1571 0.11 TYR 875 -0.15 GLU 984

SER 1162 0.11 LEU 876 -0.16 GLU 984

ASP 920 0.12 LYS 877 -0.16 GLU 984

GLN 917 0.12 GLN 878 -0.14 GLU 984

GLN 917 0.12 LEU 879 -0.15 GLU 984

GLN 917 0.15 HIS 880 -0.16 GLU 984

GLN 917 0.19 PRO 881 -0.15 GLU 984

GLN 917 0.23 VAL 882 -0.16 GLU 984

GLN 917 0.19 GLU 883 -0.18 GLU 984

ASP 920 0.18 TRP 884 -0.17 GLU 984

GLN 917 0.25 GLU 885 -0.14 GLU 984

GLN 917 0.21 CYS 886 -0.15 GLU 984

GLN 917 0.15 PHE 887 -0.19 GLU 984

ASP 920 0.19 VAL 888 -0.16 GLU 984

SER 916 0.24 LYS 889 -0.16 GLU 896

ALA 1024 0.15 ASP 890 -0.17 GLU 984

LEU 894 0.15 THR 891 -0.18 GLU 984

SER 916 0.13 LYS 892 -0.27 GLU 896

ALA 1024 0.15 ILE 893 -0.15 GLU 897

ALA 1024 0.24 LEU 894 -0.17 GLY 786

ALA 1024 0.19 ALA 895 -0.19 LYS 892

HIS 1055 0.24 GLU 896 -0.28 SER 916

ALA 1024 0.35 GLU 897 -0.21 SER 916

ALA 1024 0.36 THR 898 -0.27 SER 916

HIS 1055 0.30 ALA 899 -0.45 SER 916

HIS 1055 0.38 ALA 900 -0.36 SER 916

ARG 1023 0.45 TYR 901 -0.31 LYS 915

ASP 770 0.32 LEU 914 -0.37 ALA 899

ASP 770 0.26 LYS 915 -0.40 ALA 899

ASP 770 0.29 SER 916 -0.45 ALA 899

ASP 770 0.31 GLN 917 -0.35 ALA 899

ASP 770 0.22 ILE 918 -0.31 ALA 899

ASP 770 0.18 ASP 919 -0.33 ALA 899

GLU 885 0.24 ASP 920 -0.29 ALA 899

PRO 810 0.15 LEU 921 -0.22 ALA 899

ARG 1778 0.08 PRO 922 -0.19 LEU 857

TYR 1571 0.09 PHE 923 -0.19 GLU 896

ASP 920 0.12 TYR 924 -0.18 GLU 896

LEU 1774 0.10 CYS 925 -0.16 GLU 984

GLN 1779 0.13 ILE 926 -0.19 GLU 984

LEU 873 0.10 GLY 927 -0.20 GLU 984

SER 1786 0.13 PHE 928 -0.21 GLU 984

SER 1786 0.11 LYS 929 -0.19 GLU 984

SER 1786 0.17 SER 930 -0.21 GLU 984

SER 1786 0.24 ALA 931 -0.23 GLU 984

SER 1786 0.25 ALA 932 -0.27 GLU 984

SER 1786 0.25 PRO 933 -0.29 GLU 984

THR 898 0.34 GLU 934 -0.31 GLU 984

THR 898 0.19 TYR 935 -0.27 GLU 984

SER 1786 0.21 THR 936 -0.26 GLU 984

TYR 901 0.24 LEU 937 -0.28 GLU 984

THR 898 0.24 ARG 938 -0.27 GLU 984

SER 1786 0.14 THR 939 -0.23 GLU 984

SER 1786 0.17 ARG 940 -0.24 GLU 984

TYR 901 0.24 ILE 941 -0.23 GLU 984

TYR 901 0.17 TRP 942 -0.22 GLU 984

TYR 901 0.14 ALA 943 -0.19 GLU 984

TYR 901 0.19 SER 944 -0.19 GLU 984

TYR 901 0.19 LEU 945 -0.19 GLU 984

TYR 901 0.14 ARG 946 -0.17 GLU 984

TYR 901 0.14 SER 947 -0.16 GLU 984

TYR 901 0.16 GLN 948 -0.16 PRO 266

TYR 901 0.20 THR 949 -0.18 PRO 266

TYR 901 0.24 LEU 950 -0.20 PRO 266

TYR 901 0.26 TYR 951 -0.21 PRO 266

TYR 901 0.23 ARG 952 -0.19 PRO 266

TYR 901 0.23 THR 953 -0.20 PRO 266

TYR 901 0.27 ILE 954 -0.22 PRO 266

TYR 901 0.28 SER 955 -0.22 PRO 266

TYR 901 0.24 GLY 956 -0.20 PRO 266

TYR 901 0.25 PHE 957 -0.22 PRO 266

TYR 901 0.29 MET 958 -0.25 PRO 266

TYR 901 0.26 ASN 959 -0.22 PRO 266

TYR 901 0.24 TYR 960 -0.24 PRO 266

TYR 901 0.27 SER 961 -0.26 PRO 266

TYR 901 0.27 ARG 962 -0.24 PRO 266

TYR 901 0.22 ALA 963 -0.23 PRO 266

TYR 901 0.23 ILE 964 -0.26 PRO 266

TYR 901 0.25 LYS 965 -0.27 PRO 266

TYR 901 0.22 LEU 966 -0.24 PRO 266

TYR 901 0.19 LEU 967 -0.24 PRO 266

TYR 901 0.19 TYR 968 -0.27 PRO 266

ALA 900 0.19 ARG 969 -0.25 PRO 266

ALA 900 0.17 VAL 970 -0.23 PRO 266

ALA 900 0.16 GLU 971 -0.24 PRO 266

ALA 900 0.16 ASN 972 -0.25 PRO 266

ALA 900 0.14 PRO 973 -0.23 PRO 266

LEU 143 0.17 GLU 974 -0.25 PRO 266

LEU 143 0.17 ILE 975 -0.26 PRO 266

ALA 900 0.16 VAL 976 -0.24 PRO 266

ALA 153 0.13 GLN 977 -0.23 PRO 266

ALA 153 0.16 MET 978 -0.24 PRO 266

ASN 145 0.17 PHE 979 -0.23 PRO 266

GLU 162 0.15 GLY 980 -0.23 GLY 786

GLU 162 0.15 GLY 981 -0.30 GLY 786

GLU 162 0.17 ASN 982 -0.27 GLU 934

ALA 900 0.17 ALA 983 -0.26 GLU 934

GLU 162 0.18 GLU 984 -0.31 GLU 934

ASN 145 0.20 GLY 985 -0.29 ALA 1024

ALA 900 0.19 LEU 986 -0.25 PRO 266

TYR 901 0.24 GLU 987 -0.26 PRO 266

TYR 901 0.23 ARG 988 -0.29 ALA 1024

TYR 901 0.20 GLU 989 -0.28 PRO 266

TYR 901 0.24 LEU 990 -0.28 PRO 266

TYR 901 0.28 GLU 991 -0.29 PRO 266

TYR 901 0.24 LYS 992 -0.31 PRO 266

TYR 901 0.23 MET 993 -0.32 PRO 266

TYR 901 0.27 ALA 994 -0.32 PRO 266

TYR 901 0.29 ARG 995 -0.33 PRO 266

TYR 901 0.26 ARG 996 -0.37 PRO 266

TYR 901 0.24 LYS 997 -0.34 PRO 266

TYR 901 0.26 PHE 998 -0.31 PRO 266

TYR 901 0.27 LYS 999 -0.31 PRO 266

TYR 901 0.28 PHE 1000 -0.28 PRO 266

TYR 901 0.27 LEU 1001 -0.28 PRO 266

TYR 901 0.27 VAL 1002 -0.25 PRO 266

TYR 901 0.25 SER 1003 -0.25 PRO 266

TYR 901 0.24 MET 1004 -0.23 PRO 266

TYR 901 0.22 GLN 1005 -0.21 PRO 266

TYR 901 0.21 ARG 1006 -0.21 PRO 266

TYR 901 0.24 LEU 1007 -0.24 PRO 266

TYR 901 0.23 ALA 1008 -0.23 PRO 266

TYR 901 0.20 LYS 1009 -0.21 PRO 266

TYR 901 0.21 PHE 1010 -0.21 PRO 266

TYR 901 0.19 LYS 1011 -0.20 PRO 266

TYR 901 0.22 PRO 1012 -0.22 PRO 266

TYR 901 0.22 HIS 1013 -0.21 PRO 266

TYR 901 0.23 GLU 1014 -0.21 PRO 266

TYR 901 0.27 LEU 1015 -0.23 PRO 266

TYR 901 0.29 GLU 1016 -0.24 PRO 266

TYR 901 0.28 ASN 1017 -0.23 PRO 266

TYR 901 0.30 ALA 1018 -0.25 PRO 266

TYR 901 0.35 GLU 1019 -0.26 PRO 266

TYR 901 0.37 PHE 1020 -0.25 PRO 136

TYR 901 0.35 LEU 1021 -0.26 PRO 266

TYR 901 0.39 LEU 1022 -0.28 PRO 266

TYR 901 0.45 ARG 1023 -0.29 PRO 136

TYR 901 0.44 ALA 1024 -0.31 GLU 984

TYR 901 0.41 TYR 1025 -0.28 PRO 266

TYR 901 0.43 PRO 1026 -0.31 PRO 266

TYR 901 0.38 ASP 1027 -0.33 PRO 266

TYR 901 0.34 LEU 1028 -0.30 PRO 266

TYR 901 0.32 GLN 1029 -0.31 PRO 266

TYR 901 0.30 ILE 1030 -0.28 PRO 266

TYR 901 0.27 ALA 1031 -0.28 PRO 266

TYR 901 0.26 TYR 1032 -0.26 PRO 266

TYR 901 0.23 LEU 1033 -0.25 PRO 266

TYR 901 0.24 ASP 1034 -0.25 PRO 266

TYR 901 0.22 GLU 1035 -0.24 PRO 266

TYR 901 0.23 GLU 1036 -0.25 PRO 266

TYR 901 0.21 PRO 1037 -0.23 PRO 266

TYR 901 0.20 PRO 1038 -0.22 PRO 266

TYR 901 0.21 LEU 1039 -0.23 PRO 266

TYR 901 0.19 THR 1040 -0.21 PRO 266

TYR 901 0.18 GLU 1041 -0.20 PRO 266

TYR 901 0.17 GLY 1042 -0.18 PRO 266

TYR 901 0.18 GLU 1043 -0.19 PRO 266

TYR 901 0.18 GLU 1044 -0.19 PRO 266

TYR 901 0.20 PRO 1045 -0.21 PRO 266

TYR 901 0.21 ARG 1046 -0.24 PRO 266

TYR 901 0.22 ILE 1047 -0.24 PRO 266

TYR 901 0.24 TYR 1048 -0.27 PRO 266

TYR 901 0.25 SER 1049 -0.28 PRO 266

TYR 901 0.28 ALA 1050 -0.31 PRO 266

TYR 901 0.30 LEU 1051 -0.32 PRO 266

TYR 901 0.33 ILE 1052 -0.32 PRO 266

TYR 901 0.37 ASP 1053 -0.34 PRO 266

TYR 901 0.42 GLY 1054 -0.33 PRO 266

TYR 901 0.45 HIS 1055 -0.42 ASN 145

TYR 901 0.42 CYS 1056 -0.37 ASN 145

TYR 901 0.43 GLU 1057 -0.37 ASN 145

TYR 901 0.40 ILE 1058 -0.34 ASN 145

TYR 901 0.36 LEU 1059 -0.33 PRO 266

TYR 901 0.34 ASP 1060 -0.31 PRO 266

TYR 901 0.30 ASN 1061 -0.29 PRO 266

TYR 901 0.32 GLY 1062 -0.28 PRO 266

TYR 901 0.31 ARG 1063 -0.29 PRO 266

TYR 901 0.36 ARG 1064 -0.32 PRO 266

TYR 901 0.35 ARG 1065 -0.35 PRO 266

TYR 901 0.33 PRO 1066 -0.35 PRO 266

TYR 901 0.33 LYS 1067 -0.36 PRO 266

TYR 901 0.30 PHE 1068 -0.36 PRO 266

TYR 901 0.28 ARG 1069 -0.33 PRO 266

TYR 901 0.26 VAL 1070 -0.32 PRO 266

TYR 901 0.24 GLN 1071 -0.29 PRO 266

TYR 901 0.22 LEU 1072 -0.26 PRO 266

TYR 901 0.21 SER 1073 -0.23 PRO 266

TYR 901 0.20 GLY 1074 -0.21 PRO 266

TYR 901 0.19 ASN 1075 -0.20 PRO 266

TYR 901 0.20 PRO 1076 -0.20 PRO 266

TYR 901 0.19 ILE 1077 -0.18 PRO 266

TYR 901 0.18 LEU 1078 -0.16 PRO 266

TYR 901 0.17 GLY 1079 -0.15 PRO 266

TYR 901 0.17 ASP 1080 -0.14 PRO 266

TYR 901 0.19 GLY 1081 -0.16 PRO 266

TYR 901 0.19 LYS 1082 -0.17 PRO 266

TYR 901 0.19 SER 1083 -0.17 PRO 266

TYR 901 0.20 ASP 1084 -0.19 PRO 266

TYR 901 0.21 ASN 1085 -0.20 PRO 266

TYR 901 0.21 GLN 1086 -0.22 PRO 266

TYR 901 0.21 ASN 1087 -0.23 PRO 266

TYR 901 0.23 HIS 1088 -0.25 PRO 266

TYR 901 0.24 ALA 1089 -0.27 PRO 266

TYR 901 0.23 LEU 1090 -0.28 PRO 266

TYR 901 0.24 ILE 1091 -0.32 PRO 266

TYR 901 0.26 PHE 1092 -0.33 PRO 266

TYR 901 0.25 TYR 1093 -0.33 PRO 266

TYR 901 0.24 ARG 1094 -0.36 PRO 266

TYR 901 0.22 GLY 1095 -0.36 PRO 266

TYR 901 0.20 GLU 1096 -0.34 PRO 266

TYR 901 0.20 TYR 1097 -0.28 PRO 266

TYR 901 0.21 ILE 1098 -0.26 PRO 266

TYR 901 0.20 GLN 1099 -0.22 PRO 266

TYR 901 0.20 LEU 1100 -0.20 PRO 266

TYR 901 0.20 ILE 1101 -0.19 PRO 266

TYR 901 0.20 ASP 1102 -0.17 PRO 266

TYR 901 0.21 ALA 1103 -0.19 PRO 266

TYR 901 0.19 ASN 1104 -0.16 PRO 266

TYR 901 0.19 GLN 1105 -0.16 PRO 266

TYR 901 0.19 ASP 1106 -0.17 PRO 266

TYR 901 0.19 ASN 1107 -0.17 PRO 266

TYR 901 0.18 TYR 1108 -0.17 PRO 266

TYR 901 0.19 LEU 1109 -0.18 PRO 266

TYR 901 0.15 GLU 1110 -0.16 PRO 266

TYR 901 0.16 GLU 1111 -0.16 PRO 266

TYR 901 0.19 CYS 1112 -0.19 PRO 266

TYR 901 0.17 LEU 1113 -0.19 PRO 266

TYR 901 0.16 LYS 1114 -0.18 PRO 266

TYR 901 0.18 ILE 1115 -0.21 PRO 266

TYR 901 0.17 ARG 1116 -0.22 PRO 266

TYR 901 0.15 SER 1117 -0.18 PRO 266

TYR 901 0.16 VAL 1118 -0.18 PRO 266

TYR 901 0.17 LEU 1119 -0.21 PRO 266

TYR 901 0.15 ALA 1120 -0.20 PRO 266

TYR 901 0.14 GLU 1121 -0.15 ASP 268

TYR 901 0.15 PHE 1122 -0.18 PRO 266

TYR 901 0.13 GLU 1123 -0.18 ASP 268

TYR 901 0.14 GLU 1124 -0.23 PRO 266

MET 200 0.14 LEU 1125 -0.25 PRO 266

TYR 901 0.12 ASN 1126 -0.22 ASP 268

PRO 1147 0.13 VAL 1127 -0.24 ASP 268

GLY 615 0.13 GLU 1128 -0.29 ASP 268

THR 1144 0.15 GLN 1129 -0.37 VAL 1130

SER 591 0.08 VAL 1130 -0.37 GLN 1129

TYR 901 0.10 ASN 1131 -0.38 PRO 266

TYR 901 0.11 PRO 1132 -0.32 PRO 266

TYR 901 0.11 TYR 1133 -0.36 THR 269

PRO 418 0.11 ALA 1134 -0.36 ASP 268

GLU 416 0.12 PRO 1135 -0.47 THR 272

PRO 266 0.45 GLY 1136 -0.39 LYS 275

PRO 266 0.26 LEU 1137 -0.29 LYS 275

PRO 266 0.30 ARG 1138 -0.25 LYS 275

PRO 266 0.17 TYR 1139 -0.26 GLU 283

PRO 266 0.25 GLU 1140 -0.19 GLU 283

PRO 266 0.24 GLU 1141 -0.21 LYS 275

GLY 587 0.11 GLN 1142 -0.19 LYS 275

GLN 1129 0.11 THR 1143 -0.17 LYS 275

GLN 1129 0.15 THR 1144 -0.15 LYS 275

TYR 901 0.12 ASN 1145 -0.16 GLU 283

TYR 901 0.12 HIS 1146 -0.13 GLU 283

GLN 1129 0.14 PRO 1147 -0.26 VAL 1148

TYR 901 0.15 VAL 1148 -0.26 PRO 1147

TYR 901 0.16 ALA 1149 -0.20 PRO 1147

TYR 901 0.16 ILE 1150 -0.14 PRO 266

TYR 901 0.15 VAL 1151 -0.13 PRO 266

TYR 901 0.15 GLY 1152 -0.12 PRO 266

TYR 901 0.14 ALA 1153 -0.12 PRO 266

TYR 901 0.13 ARG 1154 -0.10 PRO 266

TYR 901 0.14 GLU 1155 -0.11 PRO 266

TYR 901 0.13 TYR 1156 -0.11 PRO 266

TYR 901 0.13 ILE 1157 -0.11 PRO 266

TYR 901 0.13 PHE 1158 -0.12 PRO 266

TYR 901 0.13 SER 1159 -0.12 PRO 266

GLN 917 0.11 GLU 1160 -0.11 GLU 984

GLN 917 0.12 ASN 1161 -0.11 GLU 984

LEU 876 0.11 SER 1162 -0.11 PHE 1772

TYR 1571 0.11 GLY 1163 -0.13 PHE 1772

TYR 1571 0.11 VAL 1164 -0.09 GLU 984

TYR 1571 0.13 LEU 1165 -0.10 ALA 1548

TYR 1571 0.11 GLY 1166 -0.09 LYS 1547

TYR 1571 0.11 ASP 1167 -0.09 GLU 984

TYR 1571 0.11 VAL 1168 -0.09 ALA 1548

TYR 1571 0.11 ALA 1169 -0.09 ALA 1548

TYR 901 0.11 ALA 1170 -0.09 PRO 266

TYR 1571 0.10 GLY 1171 -0.08 GLU 984

PHE 13 0.13 LYS 1172 -0.08 VAL 1820

TYR 901 0.12 GLU 1173 -0.08 PRO 266

TYR 901 0.11 GLN 1174 -0.08 PRO 266

TYR 901 0.11 THR 1175 -0.09 ALA 1823

TYR 901 0.12 PHE 1176 -0.08 VAL 1820

TYR 901 0.13 GLY 1177 -0.08 ALA 1823

TYR 901 0.12 THR 1178 -0.08 LYS 275

TYR 901 0.10 LEU 1179 -0.09 ALA 1823

TYR 901 0.11 PHE 1180 -0.09 ALA 1823

TYR 901 0.12 ALA 1181 -0.08 ALA 1823

TYR 901 0.11 ARG 1182 -0.09 LYS 275

TYR 901 0.10 THR 1183 -0.09 ALA 1823

TYR 901 0.12 LEU 1184 -0.09 ALA 1823

TYR 901 0.12 SER 1185 -0.09 LYS 275

TYR 901 0.11 GLN 1186 -0.10 LYS 275

TYR 901 0.11 ILE 1187 -0.09 LYS 275

TYR 901 0.12 GLY 1188 -0.09 GLU 283

TYR 901 0.13 GLY 1189 -0.08 ALA 1823

TYR 901 0.13 LYS 1190 -0.08 GLU 283

TYR 901 0.14 LEU 1191 -0.07 GLU 283

TYR 901 0.16 HIS 1192 -0.10 PRO 266

TYR 901 0.15 TYR 1193 -0.11 PRO 266

TYR 901 0.17 GLY 1194 -0.14 PRO 266

TYR 901 0.18 HIS 1195 -0.15 PRO 266

TYR 901 0.18 PRO 1196 -0.15 PRO 266

TYR 901 0.17 ASP 1197 -0.16 PRO 266

TYR 901 0.18 PHE 1198 -0.19 PRO 266

TYR 901 0.18 ILE 1199 -0.20 PRO 266

TYR 901 0.18 ASN 1200 -0.23 PRO 266

TYR 901 0.19 ALA 1201 -0.28 PRO 266

TYR 901 0.18 THR 1202 -0.29 PRO 266

TYR 901 0.17 PHE 1203 -0.22 PRO 266

TYR 901 0.17 MET 1204 -0.20 PRO 266

TYR 901 0.19 THR 1205 -0.24 PRO 266

TYR 901 0.18 THR 1206 -0.25 PRO 266

TYR 901 0.17 ARG 1207 -0.18 PRO 266

TYR 901 0.17 GLY 1208 -0.18 PRO 266

TYR 901 0.18 GLY 1209 -0.19 PRO 266

TYR 901 0.18 VAL 1210 -0.18 PRO 266

TYR 901 0.18 SER 1211 -0.16 PRO 266

TYR 901 0.17 LYS 1212 -0.14 PRO 266

TYR 901 0.18 ALA 1213 -0.14 PRO 266

TYR 901 0.17 GLN 1214 -0.12 PRO 266

TYR 901 0.17 LYS 1215 -0.12 ASP 1551

TYR 901 0.16 GLY 1216 -0.14 ASP 1551

TYR 901 0.15 LEU 1217 -0.11 ASP 1551

TYR 901 0.16 HIS 1218 -0.10 PRO 266

TYR 901 0.16 LEU 1219 -0.11 ASP 1551

TYR 901 0.16 ASN 1220 -0.10 PRO 266

TYR 901 0.17 GLU 1221 -0.12 PRO 266

TYR 901 0.17 ASP 1222 -0.12 PRO 266

TYR 901 0.16 ILE 1223 -0.09 PRO 266

TYR 901 0.16 TYR 1224 -0.09 PRO 266

TYR 901 0.17 ALA 1225 -0.12 PRO 266

TYR 901 0.16 GLY 1226 -0.09 PRO 266

TYR 901 0.15 MET 1227 -0.07 ALA 1823

TYR 901 0.16 ASN 1228 -0.08 PRO 266

TYR 901 0.15 ALA 1229 -0.09 PRO 266

TYR 901 0.14 MET 1230 -0.08 GLU 283

TYR 901 0.14 LEU 1231 -0.07 ALA 1823

TYR 901 0.15 ARG 1232 -0.08 GLU 283

TYR 901 0.14 GLY 1233 -0.11 GLU 283

TYR 901 0.15 GLY 1234 -0.11 GLU 283

TYR 901 0.14 ARG 1235 -0.11 GLU 283

TYR 901 0.14 ILE 1236 -0.10 GLU 283

TYR 901 0.13 LYS 1237 -0.10 LYS 275

TYR 901 0.13 HIS 1238 -0.10 LYS 275

TYR 901 0.13 CYS 1239 -0.11 LYS 275

TYR 901 0.12 GLU 1240 -0.10 LYS 275

TYR 901 0.12 TYR 1241 -0.11 ASP 268

TYR 901 0.14 TYR 1242 -0.13 PRO 266

TYR 901 0.14 GLN 1243 -0.13 PRO 266

TYR 901 0.16 CYS 1244 -0.15 PRO 266

TYR 901 0.16 GLY 1245 -0.14 PRO 266

TYR 901 0.16 LYS 1246 -0.14 PRO 266

TYR 901 0.16 GLY 1247 -0.13 PRO 266

TYR 901 0.14 ARG 1248 -0.12 PRO 266

TYR 901 0.14 ASP 1249 -0.12 PRO 266

SER 947 0.13 LEU 1250 -0.11 PRO 266

ARG 940 0.12 GLY 1251 -0.11 ALA 1548

TYR 1571 0.14 PHE 1252 -0.13 ASN 1490

TYR 1571 0.13 GLY 1253 -0.14 ALA 1548

TYR 901 0.14 THR 1254 -0.13 ALA 1548

TYR 1571 0.13 ILE 1255 -0.11 ALA 1548

TYR 1571 0.14 LEU 1256 -0.11 ALA 1548

TYR 901 0.14 ASN 1257 -0.13 ALA 1548

TYR 901 0.15 PHE 1258 -0.11 GLY 1550

TYR 901 0.13 THR 1259 -0.11 GLY 1550

TYR 901 0.14 THR 1260 -0.12 GLY 1550

TYR 901 0.15 LYS 1261 -0.13 GLY 1550

TYR 901 0.15 ILE 1262 -0.10 GLY 1550

TYR 901 0.14 GLY 1263 -0.10 ASP 1551

TYR 901 0.14 ALA 1264 -0.12 ASP 1551

TYR 901 0.15 GLY 1265 -0.11 ASP 1551

TYR 901 0.14 MET 1266 -0.09 ASP 1551

TYR 901 0.13 GLY 1267 -0.11 SER 1448

TYR 901 0.14 GLU 1268 -0.10 ASP 1551

TYR 901 0.14 GLN 1269 -0.09 ASP 1551

TYR 901 0.13 MET 1270 -0.09 PHE 436

TYR 901 0.14 LEU 1271 -0.10 PHE 436

TYR 901 0.15 SER 1272 -0.11 PHE 436

TYR 901 0.14 ARG 1273 -0.11 PHE 436

TYR 901 0.15 GLU 1274 -0.08 PHE 436

TYR 901 0.14 TYR 1275 -0.08 ALA 1812

TYR 901 0.13 TYR 1276 -0.08 PHE 436

TYR 901 0.14 TYR 1277 -0.07 ALA 1823

TYR 901 0.13 LEU 1278 -0.08 ALA 1823

TYR 901 0.12 GLY 1279 -0.08 ALA 1823

TYR 901 0.12 THR 1280 -0.08 ALA 1823

ASP 268 0.13 GLN 1281 -0.08 ALA 1823

TYR 901 0.12 LEU 1282 -0.10 MET 241

ASP 268 0.13 PRO 1283 -0.13 MET 241

ASP 268 0.12 VAL 1284 -0.10 MET 241

TYR 901 0.11 ASP 1285 -0.10 MET 241

TYR 901 0.12 ARG 1286 -0.11 MET 241

TYR 901 0.12 PHE 1287 -0.09 MET 241

TYR 901 0.11 LEU 1288 -0.09 ALA 1823

TYR 901 0.12 THR 1289 -0.09 ALA 1823

TYR 901 0.13 PHE 1290 -0.09 ALA 1823

TYR 901 0.12 TYR 1291 -0.09 ALA 1823

TYR 901 0.12 TYR 1292 -0.10 ALA 1823

TYR 901 0.12 ALA 1293 -0.09 ALA 1823

TYR 901 0.13 HIS 1294 -0.09 ALA 1823

TYR 901 0.13 PRO 1295 -0.09 ALA 1823

TYR 901 0.12 GLY 1296 -0.10 ALA 1823

TYR 901 0.12 PHE 1297 -0.10 ALA 1823

TYR 901 0.12 HIS 1298 -0.10 VAL 1820

TYR 901 0.12 LEU 1299 -0.10 VAL 1820

TYR 901 0.11 ASN 1300 -0.11 ALA 1823

TYR 901 0.12 ASN 1301 -0.11 VAL 1820

ILE 1570 0.12 LEU 1302 -0.11 TRP 445

ILE 1570 0.12 PHE 1303 -0.11 ALA 1823

ILE 1570 0.11 ILE 1304 -0.12 ALA 1823

GLY 1406 0.16 GLN 1305 -0.12 VAL 1820

ILE 1570 0.16 LEU 1306 -0.13 TRP 445

ILE 1570 0.13 SER 1307 -0.12 ALA 1823

VAL 1403 0.14 LEU 1308 -0.14 ALA 1823

MET 1310 0.17 GLN 1309 -0.12 ALA 1823

GLN 1309 0.17 MET 1310 -0.12 VAL 509

VAL 1403 0.12 PHE 1311 -0.13 ALA 1823

VAL 1403 0.13 MET 1312 -0.14 ALA 1823

ILE 1570 0.12 LEU 1313 -0.12 ALA 1823

ILE 1570 0.10 THR 1314 -0.13 ALA 1823

HIS 1013 0.09 LEU 1315 -0.16 ALA 1823

LEU 1482 0.10 VAL 1316 -0.15 ALA 1823

HIS 1013 0.10 ASN 1317 -0.12 ALA 1823

HIS 1013 0.09 LEU 1318 -0.15 ALA 1823

HIS 1013 0.09 SER 1319 -0.17 ALA 1823

HIS 1013 0.09 SER 1320 -0.15 ALA 1823

HIS 1013 0.09 LEU 1321 -0.14 ALA 1823

HIS 1013 0.08 ALA 1322 -0.18 ALA 1823

HIS 1013 0.08 HIS 1323 -0.21 ALA 1823

HIS 1013 0.08 GLU 1324 -0.16 ALA 1823

HIS 1013 0.08 SER 1325 -0.16 ALA 1823

HIS 1013 0.07 ILE 1326 -0.17 ALA 1823

HIS 1013 0.06 MET 1327 -0.17 ALA 1823

HIS 1013 0.06 CYS 1328 -0.17 ALA 1823

GLY 1062 0.06 ILE 1329 -0.18 ALA 1823

ASP 268 0.06 TYR 1330 -0.17 ALA 1823

ASP 268 0.06 ASP 1331 -0.16 ALA 1823

PRO 266 0.06 ARG 1332 -0.15 ALA 1823

PRO 266 0.07 ASN 1333 -0.14 ALA 1823

PRO 266 0.07 LYS 1334 -0.13 ALA 1823

PRO 266 0.08 PRO 1335 -0.12 ALA 1823

ASP 268 0.09 LYS 1336 -0.12 ALA 1823

ASP 268 0.09 THR 1337 -0.10 ALA 1823

ASP 268 0.08 ASP 1338 -0.11 ALA 1823

ASP 268 0.08 VAL 1339 -0.11 ALA 1823

ASP 268 0.07 LEU 1340 -0.12 ALA 1823

ASP 268 0.07 VAL 1341 -0.13 ALA 1823

ASP 268 0.06 PRO 1342 -0.14 HIS 1826

ASP 268 0.07 ILE 1343 -0.11 HIS 1826

ASP 268 0.08 GLY 1344 -0.10 HIS 1826

LYS 1011 0.07 CYS 1345 -0.13 ALA 1823

LYS 1011 0.07 TYR 1346 -0.13 ALA 1823

LYS 1011 0.07 ASN 1347 -0.15 ALA 1823

HIS 1013 0.07 PHE 1348 -0.16 ALA 1823

HIS 1013 0.07 GLN 1349 -0.18 ALA 1823

HIS 1013 0.07 PRO 1350 -0.16 ALA 1823

LEU 677 0.08 ALA 1351 -0.16 ALA 1823

ILE 1570 0.08 VAL 1352 -0.19 ALA 1823

GLN 917 0.07 ASP 1353 -0.19 ALA 1823

GLN 917 0.07 TRP 1354 -0.17 ALA 1823

LEU 677 0.08 VAL 1355 -0.18 ALA 1823

GLN 917 0.07 ARG 1356 -0.20 ALA 1823

GLN 917 0.08 ARG 1357 -0.17 ALA 1823

LEU 677 0.08 TYR 1358 -0.16 ALA 1823

GLN 917 0.08 THR 1359 -0.18 ALA 1823

GLN 917 0.08 LEU 1360 -0.18 ALA 1823

GLN 917 0.08 SER 1361 -0.16 ALA 1823

PHE 1366 0.09 ILE 1362 -0.16 ALA 1823

GLN 917 0.09 PHE 1363 -0.17 ALA 1823

GLN 917 0.09 ILE 1364 -0.16 ALA 1823

GLN 917 0.08 VAL 1365 -0.14 ALA 1823

ILE 1362 0.09 PHE 1366 -0.14 ALA 1823

GLN 917 0.10 TRP 1367 -0.14 ALA 1823

GLN 917 0.09 ILE 1368 -0.13 ALA 1823

GLN 917 0.09 ALA 1369 -0.12 ALA 1823

GLN 917 0.10 PHE 1370 -0.12 ALA 1823

GLN 917 0.10 VAL 1371 -0.12 ALA 1823

GLN 917 0.10 PRO 1372 -0.11 ALA 1823

GLN 917 0.11 ILE 1373 -0.10 ALA 1823

GLN 917 0.11 VAL 1374 -0.10 ALA 1823

LEU 914 0.11 VAL 1375 -0.10 ALA 1823

GLN 917 0.12 GLN 1376 -0.09 ALA 1823

GLN 917 0.13 GLU 1377 -0.09 ALA 1823

LEU 914 0.13 LEU 1378 -0.10 ALA 1823

LEU 914 0.13 ILE 1379 -0.09 ALA 1823

LEU 914 0.14 GLU 1380 -0.09 LYS 275

LEU 914 0.15 ARG 1381 -0.09 ALA 1823

LEU 914 0.15 GLY 1382 -0.09 ALA 1823

LEU 914 0.14 LEU 1383 -0.10 ALA 1823

LEU 914 0.15 TRP 1384 -0.10 ALA 1823

GLN 917 0.15 LYS 1385 -0.09 ALA 1823

GLN 917 0.13 ALA 1386 -0.10 ALA 1823

LEU 914 0.13 THR 1387 -0.10 ALA 1823

GLN 917 0.14 GLN 1388 -0.10 VAL 1820

GLN 917 0.13 ARG 1389 -0.10 VAL 1820

GLN 917 0.11 PHE 1390 -0.11 VAL 1820

GLN 917 0.11 PHE 1391 -0.11 LEU 1757

GLN 917 0.11 CYS 1392 -0.11 LEU 1757

GLN 917 0.10 HIS 1393 -0.11 LEU 1757

TYR 1571 0.10 LEU 1394 -0.13 LEU 1757

ALA 1477 0.11 LEU 1395 -0.15 LEU 1757

ALA 1477 0.11 SER 1396 -0.14 LEU 1757

ALA 1477 0.13 LEU 1397 -0.15 LEU 1757

TYR 1571 0.12 SER 1398 -0.11 LEU 1757

TYR 1571 0.13 PRO 1399 -0.12 VAL 1820

TYR 1571 0.14 MET 1400 -0.12 CYS 1753

TYR 1571 0.13 PHE 1401 -0.10 GLN 1754

TYR 1571 0.14 GLU 1402 -0.10 VAL 1820

TYR 1571 0.16 VAL 1403 -0.11 VAL 1820

TYR 1571 0.16 PHE 1404 -0.10 ALA 1812

TYR 1571 0.15 ALA 1405 -0.09 GLY 1550

TYR 1571 0.16 GLY 1406 -0.10 TYR 1409

TYR 1571 0.19 GLN 1407 -0.12 SER 1410

TYR 1571 0.16 ILE 1408 -0.12 ALA 1412

PRO 1567 0.15 TYR 1409 -0.11 ILE 1408

PRO 1567 0.18 SER 1410 -0.12 GLN 1407

PRO 1567 0.20 SER 1411 -0.19 SER 1448

PRO 1567 0.15 ALA 1412 -0.14 SER 1448

PRO 1567 0.14 LEU 1413 -0.11 SER 1448

ALA 1563 0.20 LEU 1414 -0.13 SER 1448

ALA 1563 0.21 SER 1415 -0.15 SER 1448

TYR 901 0.14 ASP 1416 -0.12 ALA 1552

TYR 901 0.13 LEU 1417 -0.13 ARG 443

ASN 1559 0.18 ALA 1418 -0.14 SER 1448

TYR 901 0.13 ILE 1419 -0.16 ARG 1532

TYR 901 0.14 GLY 1420 -0.17 ALA 1552

TYR 901 0.15 GLY 1421 -0.19 ASP 1551

TYR 901 0.16 ALA 1422 -0.18 ASP 1551

TYR 901 0.17 ARG 1423 -0.22 ASP 1551

TYR 901 0.18 TYR 1424 -0.17 GLY 1550

ALA 850 0.19 ILE 1425 -0.17 GLY 1550

ALA 850 0.26 SER 1426 -0.16 LYS 1547

TYR 901 0.17 THR 1427 -0.14 PRO 266

TYR 901 0.18 GLY 1428 -0.15 PRO 266

TYR 901 0.16 ARG 1429 -0.14 PRO 266

LEU 855 0.15 GLY 1430 -0.14 PRO 266

ARG 940 0.13 PHE 1431 -0.13 PRO 266

LEU 857 0.13 ALA 1432 -0.12 PRO 266

LEU 857 0.14 THR 1433 -0.11 PRO 266

ASP 864 0.16 SER 1434 -0.12 GLU 1544

ASP 864 0.14 ARG 1435 -0.11 GLU 1544

ASP 865 0.19 ILE 1436 -0.13 ALA 1548

ASP 865 0.19 PRO 1437 -0.14 ASN 1520

ASP 865 0.14 PHE 1438 -0.12 ASN 1520

HIS 1013 0.14 SER 1439 -0.16 ASN 1520

HIS 1013 0.15 ILE 1440 -0.16 ASN 1520

HIS 1013 0.14 LEU 1441 -0.13 ALA 1548

ILE 1680 0.15 TYR 1442 -0.10 ALA 1548

THR 1606 0.15 SER 1443 -0.12 ALA 1548

LYS 1011 0.15 ARG 1444 -0.14 GLY 1550

HIS 1013 0.14 PHE 1445 -0.11 GLY 1550

ILE 1680 0.15 ALA 1446 -0.10 ILE 1419

ARG 1684 0.17 GLY 1447 -0.14 SER 1415

TYR 1571 0.17 SER 1448 -0.19 SER 1411

TYR 1571 0.17 ALA 1449 -0.16 SER 1411

GLN 1681 0.15 ILE 1450 -0.11 SER 1411

GLN 1681 0.20 TYR 1451 -0.11 ALA 1418

TYR 1571 0.22 MET 1452 -0.12 ALA 1418

TYR 1571 0.16 GLY 1453 -0.12 ALA 1812

ILE 1483 0.28 ALA 1454 -0.14 ALA 1742

ILE 1483 0.18 ARG 1455 -0.11 TRP 445

LEU 1482 0.15 SER 1456 -0.12 TRP 445

SER 1481 0.14 MET 1457 -0.14 ILE 1815

ILE 1483 0.12 LEU 1458 -0.14 ILE 1815

ILE 1483 0.10 MET 1459 -0.12 ALA 1823

HIS 1767 0.10 LEU 1460 -0.16 ALA 1823

HIS 1767 0.10 LEU 1461 -0.19 VAL 1820

LEU 857 0.09 PHE 1462 -0.17 ALA 1823

LEU 857 0.09 GLY 1463 -0.19 ALA 1823

PHE 1766 0.09 THR 1464 -0.24 ALA 1823

PHE 1766 0.09 VAL 1465 -0.29 ALA 1823

LEU 857 0.08 ALA 1466 -0.25 ALA 1823

LEU 857 0.07 HIS 1467 -0.26 ALA 1823

LEU 857 0.07 TRP 1468 -0.29 ALA 1823

LEU 857 0.07 GLN 1469 -0.25 ALA 1823

GLN 917 0.07 ALA 1470 -0.25 ALA 1823

LEU 1472 0.08 PRO 1471 -0.21 ALA 1823

MET 1770 0.08 LEU 1472 -0.22 ALA 1823

MET 1770 0.10 LEU 1473 -0.23 VAL 1820

LEU 1395 0.10 TRP 1474 -0.19 VAL 1820

LEU 1397 0.10 PHE 1475 -0.17 VAL 1820

MET 1770 0.11 TRP 1476 -0.20 VAL 1820

LEU 1397 0.13 ALA 1477 -0.19 VAL 1820

MET 1400 0.13 SER 1478 -0.15 VAL 1820

SER 1481 0.16 LEU 1479 -0.15 ALA 1812

SER 1481 0.23 SER 1480 -0.18 ALA 1812

SER 1480 0.23 SER 1481 -0.11 ALA 1812

ALA 1454 0.18 LEU 1482 -0.11 SER 1411

ALA 1454 0.28 ILE 1483 -0.12 ALA 1812

ALA 1454 0.19 PHE 1484 -0.13 ILE 1750

ALA 1454 0.14 ALA 1485 -0.09 ALA 1812

TYR 1571 0.13 PRO 1486 -0.11 ALA 1548

ASN 1490 0.17 PHE 1487 -0.10 ALA 1548

ASN 1490 0.15 VAL 1488 -0.12 GLN 1754

LEU 857 0.13 PHE 1489 -0.10 ALA 1548

PHE 1487 0.17 ASN 1490 -0.13 PHE 1252

LEU 857 0.12 PRO 1491 -0.11 ALA 1548

GLU 863 0.12 HIS 1492 -0.10 PRO 266

ILE 1680 0.11 GLN 1493 -0.10 ALA 1548

GLN 866 0.11 PHE 1494 -0.11 SER 1396

GLN 866 0.14 ALA 1495 -0.12 ARG 1791

GLN 866 0.14 TRP 1496 -0.16 ARG 1791

GLN 866 0.18 GLU 1497 -0.16 ARG 1791

GLN 866 0.22 ASP 1498 -0.09 PRO 266

GLN 866 0.17 PHE 1499 -0.09 PRO 266

GLN 866 0.17 PHE 1500 -0.08 PRO 266

GLN 866 0.20 LEU 1501 -0.09 PRO 266

GLN 866 0.19 ASP 1502 -0.09 PRO 266

GLN 866 0.15 TYR 1503 -0.08 PRO 266

GLN 866 0.15 ARG 1504 -0.09 LYS 1637

ASP 865 0.15 ASP 1505 -0.11 LYS 1637

ASP 865 0.13 TYR 1506 -0.10 TRP 1509

HIS 1013 0.12 ILE 1507 -0.09 LYS 1637

PRO 1012 0.13 ARG 1508 -0.10 LYS 1637

PRO 1012 0.14 TRP 1509 -0.10 TYR 1506

THR 1606 0.13 LEU 1510 -0.10 SER 1640

ASN 1061 0.12 SER 1511 -0.15 SER 1640

ASN 1061 0.13 ARG 1512 -0.12 LYS 1637

ASN 1061 0.13 GLY 1513 -0.10 PRO 266

VAL 1837 0.12 ASN 1514 -0.12 THR 1706

VAL 1837 0.12 ASN 1515 -0.13 GLY 1632

LYS 1788 0.13 GLN 1516 -0.10 PRO 266

ASN 1061 0.14 TYR 1517 -0.11 PRO 266

ASN 1061 0.15 HIS 1518 -0.11 PRO 266

PRO 1012 0.17 ARG 1519 -0.13 ILE 1440

PRO 1012 0.17 ASN 1520 -0.16 SER 1439

PRO 1012 0.15 SER 1521 -0.12 SER 1439

THR 1606 0.14 TRP 1522 -0.08 PRO 266

THR 1606 0.14 ILE 1523 -0.09 GLU 409

LYS 1011 0.14 GLY 1524 -0.09 PRO 266

LYS 1011 0.15 TYR 1525 -0.09 SER 1443

LYS 1011 0.14 VAL 1526 -0.09 GLY 411

VAL 1836 0.14 ARG 1527 -0.09 GLU 409

LYS 1011 0.16 MET 1528 -0.11 GLY 1447

LYS 1011 0.16 SER 1529 -0.13 GLY 1447

VAL 1836 0.14 ARG 1530 -0.10 GLY 411

LYS 1011 0.14 ALA 1531 -0.11 GLU 381

LYS 1011 0.15 ARG 1532 -0.16 ILE 1419

TRP 663 0.14 ILE 1533 -0.11 ASP 432

VAL 1836 0.15 THR 1534 -0.12 ASP 432

VAL 1836 0.14 GLY 1535 -0.13 GLU 381

VAL 1836 0.14 PHE 1536 -0.14 GLU 381

VAL 1836 0.14 LYS 1537 -0.13 GLU 371

VAL 1836 0.13 ARG 1538 -0.17 GLU 371

VAL 1836 0.13 LYS 1539 -0.20 VAL 373

VAL 1836 0.13 LEU 1540 -0.21 ASP 374

VAL 1836 0.13 VAL 1541 -0.20 ASP 374

VAL 1836 0.12 GLY 1542 -0.19 ASP 374

ASN 1061 0.12 ASP 1543 -0.14 ASP 374

ASN 1061 0.14 GLU 1544 -0.14 PRO 266

ASN 1061 0.14 SER 1545 -0.13 PRO 266

ASN 1061 0.14 GLU 1546 -0.14 VAL 378

ASN 1061 0.16 LYS 1547 -0.16 SER 1426

ASN 1061 0.17 ALA 1548 -0.16 ILE 1425

LYS 1011 0.16 ALA 1549 -0.13 ARG 1423

LYS 1011 0.18 GLY 1550 -0.20 ARG 1423

LYS 1009 0.17 ASP 1551 -0.22 ARG 1423

LYS 1009 0.15 ALA 1552 -0.17 GLY 1421

TYR 901 0.14 SER 1553 -0.13 GLU 381

TRP 663 0.14 ARG 1554 -0.13 ASP 432

TRP 663 0.14 ALA 1555 -0.13 ASP 432

TRP 663 0.15 HIS 1556 -0.14 ASP 433

TRP 663 0.17 ARG 1557 -0.14 GLY 411

TRP 663 0.17 THR 1558 -0.14 GLY 411

ALA 1418 0.18 ASN 1559 -0.12 GLY 411

TRP 663 0.15 LEU 1560 -0.11 GLY 411

TRP 663 0.18 ILE 1561 -0.12 GLY 411

ALA 1418 0.16 MET 1562 -0.12 SER 516

SER 1415 0.21 ALA 1563 -0.11 CYS 513

SER 1411 0.16 GLU 1564 -0.10 GLY 411

TRP 663 0.17 ILE 1565 -0.11 GLY 411

TRP 664 0.17 ILE 1566 -0.11 LEU 512

SER 1411 0.20 PRO 1567 -0.12 VAL 509

SER 1411 0.18 CYS 1568 -0.10 VAL 509

ALA 1573 0.22 ALA 1569 -0.10 GLY 411

GLN 1407 0.17 ILE 1570 -0.11 VAL 509

MET 1452 0.22 TYR 1571 -0.11 VAL 509

MET 1452 0.20 ALA 1572 -0.09 VAL 509

ALA 1569 0.22 ALA 1573 -0.08 CYS 536

MET 1452 0.15 GLY 1574 -0.09 VAL 509

MET 1452 0.16 CYS 1575 -0.09 VAL 509

MET 1452 0.14 PHE 1576 -0.07 CYS 536

MET 1452 0.12 ILE 1577 -0.08 CYS 536

MET 1452 0.11 ALA 1578 -0.09 ALA 1823

LYS 1011 0.11 PHE 1579 -0.07 ALA 1823

CYS 1682 0.13 THR 1580 -0.06 ALA 1823

LYS 1011 0.11 PHE 1581 -0.09 ALA 1823

LYS 1011 0.10 ILE 1582 -0.11 ALA 1823

LYS 1011 0.10 ASN 1583 -0.08 ALA 1823

MET 1690 0.10 ALA 1584 -0.07 ALA 1823

MET 1690 0.09 GLN 1585 -0.09 HIS 1826

LYS 1011 0.08 THR 1586 -0.11 HIS 1826

ASP 1850 0.10 GLY 1587 -0.12 HIS 1826

SER 1727 0.08 VAL 1588 -0.12 HIS 1826

SER 1727 0.10 LYS 1589 -0.10 HIS 1826

MET 1694 0.11 THR 1590 -0.08 HIS 1826

MET 1694 0.13 THR 1591 -0.05 HIS 1826

MET 1694 0.15 ASP 1592 -0.04 ASP 1834

SER 1727 0.15 ASP 1593 -0.07 ASP 1834

SER 1727 0.14 ASP 1594 -0.07 ASP 1834

MET 1694 0.15 ARG 1595 -0.04 VAL 1465

ALA 1608 0.15 VAL 1596 -0.05 ALA 1466

ALA 1608 0.17 ASN 1597 -0.04 ALA 1466

MET 1690 0.13 SER 1598 -0.04 GLY 411

MET 1690 0.17 VAL 1599 -0.04 GLY 411

LEU 1607 0.18 LEU 1600 -0.04 GLY 411

ALA 1608 0.17 ARG 1601 -0.05 GLY 411

CYS 1682 0.16 ILE 1602 -0.06 GLY 411

LEU 1607 0.29 ILE 1603 -0.05 GLY 411

ALA 1608 0.35 ILE 1604 -0.05 GLY 411

ALA 1608 0.17 CYS 1605 -0.07 GLY 411

ALA 1742 0.23 THR 1606 -0.07 GLY 411

ILE 1603 0.29 LEU 1607 -0.07 GLY 411

ILE 1604 0.35 ALA 1608 -0.08 GLY 411

ILE 1604 0.19 PRO 1609 -0.08 GLY 411

VAL 1734 0.19 ILE 1610 -0.09 GLY 411

VAL 1837 0.24 ALA 1611 -0.09 GLY 411

VAL 1837 0.21 VAL 1612 -0.09 GLY 411

VAL 1837 0.17 ASN 1613 -0.10 GLY 411

VAL 1837 0.20 LEU 1614 -0.10 GLY 411

LEU 1833 0.21 GLY 1615 -0.10 GLY 411

LEU 1833 0.18 VAL 1616 -0.09 GLY 411

VAL 1837 0.18 LEU 1617 -0.10 GLY 411

LEU 1833 0.21 PHE 1618 -0.10 ASP 410

LEU 1833 0.19 PHE 1619 -0.10 ASP 410

LEU 1833 0.16 CYS 1620 -0.09 ASP 410

LEU 1833 0.17 MET 1621 -0.10 ASP 410

LEU 1833 0.18 GLY 1622 -0.10 ASP 410

LEU 1833 0.16 MET 1623 -0.09 ASP 410

LEU 1833 0.15 SER 1624 -0.09 ASP 410

LEU 1833 0.16 CYS 1625 -0.10 ASP 410

LEU 1833 0.16 CYS 1626 -0.09 ASP 410

LEU 1833 0.15 SER 1627 -0.09 ASP 410

LEU 1833 0.14 GLY 1628 -0.10 ASN 1515

LEU 1833 0.13 PRO 1629 -0.10 ASN 1515

LEU 1833 0.12 LEU 1630 -0.10 LEU 914

LEU 1833 0.12 PHE 1631 -0.10 LEU 914

LEU 1833 0.11 GLY 1632 -0.13 ASN 1515

LEU 1833 0.10 MET 1633 -0.12 LEU 914

LEU 1833 0.10 CYS 1634 -0.11 LEU 914

LEU 1833 0.09 CYS 1635 -0.11 LEU 914

ASP 1060 0.10 LYS 1636 -0.11 LEU 914

ASP 1060 0.10 LYS 1637 -0.12 ARG 1512

LEU 1833 0.11 THR 1638 -0.09 PRO 266

VAL 1837 0.11 GLY 1639 -0.11 ASN 1514

ASN 1061 0.11 SER 1640 -0.15 SER 1511

ASP 1060 0.11 VAL 1641 -0.08 PRO 266

LEU 1833 0.12 MET 1642 -0.08 ASP 410

VAL 1837 0.11 ALA 1643 -0.08 GLY 411

ASN 1061 0.11 GLY 1644 -0.08 GLY 411

ASN 1061 0.11 ILE 1645 -0.08 GLY 411

VAL 1837 0.13 ALA 1646 -0.09 GLY 411

VAL 1837 0.11 HIS 1647 -0.09 GLY 411

ASN 1061 0.11 GLY 1648 -0.08 GLY 411

GLY 1830 0.12 VAL 1649 -0.09 GLY 411

VAL 1837 0.13 ALA 1650 -0.09 GLY 411

ASN 1061 0.11 VAL 1651 -0.09 GLY 411

ASN 1061 0.10 ILE 1652 -0.08 GLY 411

GLY 1830 0.12 VAL 1653 -0.08 GLY 411

HIS 1013 0.11 HIS 1654 -0.08 GLY 411

HIS 1013 0.10 ILE 1655 -0.08 LEU 1458

ALA 1821 0.12 ALA 1656 -0.08 GLY 411

GLY 1830 0.12 PHE 1657 -0.08 GLY 411

MET 1661 0.10 PHE 1658 -0.08 VAL 1465

ALA 1821 0.11 ILE 1659 -0.08 VAL 1465

VAL 1663 0.18 VAL 1660 -0.07 GLY 411

HIS 1013 0.11 MET 1661 -0.06 GLY 411

HIS 1013 0.09 TRP 1662 -0.10 VAL 1465

VAL 1660 0.18 VAL 1663 -0.09 VAL 1465

ALA 1608 0.14 LEU 1664 -0.07 VAL 1465

ALA 1608 0.10 GLU 1665 -0.09 VAL 1465

ALA 1608 0.09 SER 1666 -0.11 VAL 1465

ASN 1061 0.08 PHE 1667 -0.14 VAL 1465

ASN 1061 0.07 ASN 1668 -0.22 SER 1822

HIS 1013 0.07 PHE 1669 -0.22 VAL 1465

HIS 1013 0.08 VAL 1670 -0.18 SER 1822

HIS 1013 0.09 ARG 1671 -0.11 ALA 1823

HIS 1013 0.10 MET 1672 -0.08 VAL 509

CYS 1753 0.11 LEU 1673 -0.10 ALA 1823

ILE 1483 0.11 ILE 1674 -0.09 VAL 509

VAL 1749 0.11 GLY 1675 -0.08 VAL 509

VAL 1749 0.15 VAL 1676 -0.08 VAL 509

ILE 1483 0.16 VAL 1677 -0.10 VAL 509

TYR 1451 0.17 THR 1678 -0.09 VAL 509

LEU 1746 0.16 CYS 1679 -0.08 GLY 411

TYR 1451 0.20 ILE 1680 -0.08 VAL 509

TYR 1451 0.20 GLN 1681 -0.09 VAL 509

ILE 1603 0.16 CYS 1682 -0.09 GLY 411

THR 1606 0.19 GLN 1683 -0.09 GLY 411

GLY 1447 0.17 ARG 1684 -0.09 GLY 411

TRP 663 0.16 LEU 1685 -0.10 GLY 411

ILE 1603 0.20 ILE 1686 -0.10 GLY 411

VAL 1836 0.16 PHE 1687 -0.10 GLY 411

TRP 663 0.17 HIS 1688 -0.11 GLY 411

TRP 663 0.21 CYS 1689 -0.12 GLY 411

VAL 1836 0.22 MET 1690 -0.12 GLY 411

VAL 1836 0.18 THR 1691 -0.12 GLY 411

TRP 663 0.18 ALA 1692 -0.12 GLY 411

TRP 663 0.22 LEU 1693 -0.14 GLY 411

VAL 1836 0.22 MET 1694 -0.14 GLY 411

VAL 1836 0.19 LEU 1695 -0.13 GLY 411

VAL 1836 0.18 THR 1696 -0.14 GLU 409

VAL 1836 0.17 ARG 1697 -0.14 GLU 409

VAL 1836 0.16 GLU 1698 -0.12 GLU 409

VAL 1836 0.15 PHE 1699 -0.12 VAL 373

VAL 1836 0.13 LYS 1700 -0.13 VAL 378

VAL 1836 0.13 ASN 1701 -0.13 ASP 374

VAL 1836 0.13 ASP 1702 -0.11 ASP 374

VAL 1836 0.14 HIS 1703 -0.12 ASP 374

VAL 1836 0.16 ALA 1704 -0.11 ASP 374

VAL 1836 0.15 ASN 1705 -0.09 GLU 409

VAL 1836 0.13 THR 1706 -0.12 ASN 1514

VAL 1836 0.15 ALA 1707 -0.10 ASP 374

VAL 1837 0.16 PHE 1708 -0.10 GLU 409

VAL 1837 0.14 TRP 1709 -0.09 ASP 410

VAL 1837 0.13 THR 1710 -0.09 PRO 266

GLY 1835 0.15 GLY 1711 -0.09 ASP 410

GLY 1835 0.15 LYS 1712 -0.10 ASP 374

GLY 1835 0.16 TRP 1713 -0.11 ASP 374

GLY 1835 0.16 TYR 1714 -0.11 ASP 374

GLY 1835 0.18 MET 1721 -0.14 GLU 409

GLY 1835 0.18 ALA 1722 -0.13 GLU 409

GLY 1835 0.20 TRP 1723 -0.13 ASP 410

VAL 1836 0.21 THR 1724 -0.14 ASP 410

VAL 1836 0.19 GLN 1725 -0.13 GLU 409

VAL 1836 0.20 PRO 1726 -0.12 ASP 410

VAL 1836 0.22 SER 1727 -0.12 ASP 410

VAL 1836 0.21 ARG 1728 -0.13 GLU 409

VAL 1836 0.19 GLU 1729 -0.11 GLU 409

VAL 1836 0.20 LEU 1730 -0.11 ASP 410

VAL 1836 0.21 THR 1731 -0.12 GLY 411

VAL 1836 0.19 ALA 1732 -0.11 GLY 411

VAL 1837 0.17 LYS 1733 -0.10 GLY 411

VAL 1837 0.20 VAL 1734 -0.10 GLY 411

THR 1606 0.20 ILE 1735 -0.11 GLY 411

THR 1606 0.16 GLU 1736 -0.10 GLY 411

THR 1606 0.16 LEU 1737 -0.09 GLY 411

THR 1606 0.21 SER 1738 -0.09 GLY 411

THR 1606 0.21 GLU 1739 -0.11 ALA 1454

THR 1606 0.17 PHE 1740 -0.09 GLY 411

THR 1606 0.20 ALA 1741 -0.10 ALA 1454

THR 1606 0.23 ALA 1742 -0.14 ALA 1454

THR 1606 0.18 ASP 1743 -0.09 SER 1480

THR 1606 0.16 PHE 1744 -0.09 SER 1480

THR 1606 0.17 VAL 1745 -0.11 SER 1480

ILE 1680 0.18 LEU 1746 -0.13 SER 1480

THR 1606 0.15 GLY 1747 -0.10 SER 1480

THR 1606 0.14 HIS 1748 -0.11 SER 1480

VAL 1676 0.15 VAL 1749 -0.16 SER 1480

VAL 1677 0.15 ILE 1750 -0.14 SER 1480

THR 1606 0.13 LEU 1751 -0.09 PHE 1484

VAL 1676 0.12 ILE 1752 -0.12 ALA 1477

VAL 1677 0.14 CYS 1753 -0.14 ALA 1477

VAL 1677 0.12 GLN 1754 -0.12 LEU 1397

VAL 1677 0.10 LEU 1755 -0.11 LEU 1397

VAL 1677 0.10 PRO 1756 -0.13 LEU 1397

VAL 1677 0.12 LEU 1757 -0.15 LEU 1397

VAL 1677 0.10 ILE 1758 -0.13 ARG 1791

ALA 932 0.09 ILE 1759 -0.15 ARG 1791

VAL 1677 0.09 ILE 1760 -0.16 ARG 1791

ALA 931 0.09 PRO 1761 -0.19 ARG 1791

VAL 1677 0.09 LYS 1762 -0.18 ARG 1791

VAL 1677 0.11 ILE 1763 -0.15 ARG 1791

VAL 1677 0.10 ASP 1764 -0.14 ARG 1791

VAL 1677 0.10 LYS 1765 -0.15 ARG 1791

VAL 1677 0.11 PHE 1766 -0.14 ARG 1791

ALA 1454 0.12 HIS 1767 -0.12 ARG 1791

ALA 1454 0.11 SER 1768 -0.10 GLU 984

SER 1480 0.10 ILE 1769 -0.11 GLU 984

SER 1480 0.13 MET 1770 -0.10 GLU 984

SER 1480 0.12 LEU 1771 -0.11 GLY 1163

TYR 1571 0.11 PHE 1772 -0.13 GLY 1163

TYR 1571 0.10 TRP 1773 -0.12 GLU 984

CYS 925 0.10 LEU 1774 -0.13 GLU 984

TYR 1571 0.10 LYS 1775 -0.13 GLU 984

VAL 1677 0.09 PRO 1776 -0.12 GLU 984

CYS 925 0.09 SER 1777 -0.13 GLU 984

ILE 926 0.10 ARG 1778 -0.12 GLU 984

ILE 926 0.13 GLN 1779 -0.13 GLU 984

ILE 926 0.11 ILE 1780 -0.12 GLU 984

ALA 932 0.11 ARG 1781 -0.13 ILE 1784

ALA 932 0.12 PRO 1782 -0.15 ILE 1784

ALA 932 0.15 PRO 1783 -0.12 PRO 266

ALA 931 0.20 ILE 1784 -0.15 PRO 1782

GLN 866 0.25 TYR 1785 -0.14 LEU 914

ALA 932 0.25 SER 1786 -0.17 LEU 914

ALA 932 0.23 LEU 1787 -0.18 LYS 1762

PRO 933 0.22 LYS 1788 -0.16 LEU 914

GLN 866 0.27 GLN 1789 -0.14 LEU 914

ALA 932 0.18 THR 1790 -0.16 LYS 1762

ALA 932 0.18 ARG 1791 -0.23 LYS 1794

GLN 866 0.20 LEU 1792 -0.12 LYS 1794

GLN 866 0.21 ARG 1793 -0.09 LYS 1762

GLN 866 0.17 LYS 1794 -0.23 ARG 1791

GLN 866 0.15 ARG 1795 -0.10 PRO 1761

GLN 866 0.16 MET 1796 -0.08 PRO 266

GLN 866 0.16 VAL 1797 -0.09 PRO 1761

GLN 866 0.13 LYS 1798 -0.10 PRO 1761

GLN 866 0.12 LYS 1799 -0.08 PRO 266

GLN 866 0.13 TYR 1800 -0.08 PRO 266

GLN 866 0.12 CYS 1801 -0.09 LEU 1397

GLN 866 0.11 SER 1802 -0.08 ALA 1477

GLN 866 0.11 LEU 1803 -0.08 ALA 1477

GLN 866 0.11 TYR 1804 -0.09 ALA 1477

GLN 866 0.10 PHE 1805 -0.10 ALA 1477

ALA 932 0.10 LEU 1806 -0.10 ALA 1477

ALA 932 0.09 VAL 1807 -0.11 SER 1480

ALA 932 0.09 LEU 1808 -0.13 ALA 1477

ALA 932 0.09 ALA 1809 -0.12 LEU 1473

ALA 932 0.08 ILE 1810 -0.12 TRP 1476

ALA 932 0.08 PHE 1811 -0.14 SER 1480

ALA 932 0.07 ALA 1812 -0.18 TRP 1476

ALA 1656 0.09 GLY 1813 -0.16 LEU 1473

ALA 1656 0.12 CYS 1814 -0.14 LEU 1473

ILE 1659 0.09 ILE 1815 -0.17 LEU 1461

ILE 1659 0.07 ILE 1816 -0.19 VAL 1465

ALA 1656 0.09 GLY 1817 -0.17 VAL 1465

VAL 1660 0.10 PRO 1818 -0.19 VAL 1465

VAL 1660 0.07 ALA 1819 -0.25 VAL 1465

VAL 1660 0.10 VAL 1820 -0.26 VAL 1465

VAL 1660 0.15 ALA 1821 -0.22 VAL 1465

VAL 1660 0.11 SER 1822 -0.26 VAL 1465

VAL 1660 0.09 ALA 1823 -0.29 TRP 1468

PHE 1619 0.12 LYS 1824 -0.24 TRP 1468

VAL 1660 0.14 ILE 1825 -0.20 TRP 1468

GLY 1615 0.13 HIS 1826 -0.24 ASN 1845

GLY 1615 0.15 LYS 1827 -0.18 ASN 1845

ALA 1608 0.16 HIS 1828 -0.12 TRP 1468

ALA 1608 0.18 ILE 1829 -0.10 VAL 1465

ALA 1608 0.20 GLY 1830 -0.08 VAL 1465

GLY 1615 0.18 ASP 1831 -0.08 TRP 1468

GLY 1615 0.20 SER 1832 -0.07 TRP 1468

ALA 1611 0.21 LEU 1833 -0.06 VAL 1465

SER 1727 0.21 ASP 1834 -0.07 ASP 1593

SER 1727 0.22 GLY 1835 -0.07 ASP 1593

MET 1694 0.22 VAL 1836 -0.07 HIS 1838

ALA 1608 0.24 VAL 1837 -0.10 HIS 1838

ALA 1608 0.19 HIS 1838 -0.10 VAL 1837

ALA 1608 0.17 ASN 1839 -0.06 VAL 1465

ALA 1608 0.21 LEU 1840 -0.06 VAL 1465

ALA 1608 0.18 PHE 1841 -0.08 SER 1666

ALA 1608 0.14 GLN 1842 -0.09 VAL 1465

ALA 1608 0.12 PRO 1843 -0.10 VAL 1465

ALA 1608 0.10 ILE 1844 -0.17 HIS 1826

ALA 1608 0.09 ASN 1845 -0.24 HIS 1826

ALA 1608 0.09 THR 1846 -0.24 THR 1847

ALA 1608 0.07 THR 1847 -0.24 THR 1846

ALA 1608 0.07 ASN 1848 -0.16 HIS 1826

ASN 1061 0.07 ASN 1849 -0.15 HIS 1826

GLY 1587 0.10 ASP 1850 -0.13 HIS 1826

CYS 1689 0.07 THR 1851 -0.12 HIS 1826

MET 1694 0.06 GLY 1852 -0.12 HIS 1826

ASP 268 0.07 SER 1853 -0.11 HIS 1826

ASP 268 0.08 GLN 1854 -0.11 HIS 1826

ASP 268 0.08 MET 1855 -0.10 HIS 1826

ASP 268 0.09 SER 1856 -0.09 HIS 1826

PRO 266 0.07 PHE 1 -0.14 ALA 1823

PRO 266 0.08 PHE 2 -0.14 ALA 1823

PRO 266 0.07 PHE 3 -0.14 ALA 1823

LEU 914 0.07 PHE 4 -0.16 ALA 1823

LEU 914 0.08 PHE 5 -0.16 ALA 1823

LEU 914 0.08 PHE 6 -0.15 ALA 1823

GLN 917 0.08 PHE 7 -0.14 ALA 1823

GLN 917 0.08 PHE 8 -0.14 ALA 1823

TYR 901 0.09 PHE 9 -0.14 ALA 1823

ILE 1570 0.12 PHE 10 -0.13 VAL 1820

ILE 1570 0.11 PHE 11 -0.13 VAL 1820

ILE 1570 0.10 PHE 12 -0.12 VAL 1820

LYS 1172 0.13 PHE 13 -0.10 VAL 1820

TYR 901 0.12 PHE 14 -0.09 VAL 1820

TYR 901 0.14 PHE 15 -0.08 GLY 1550

TYR 901 0.15 PHE 16 -0.10 PRO 266

TYR 901 0.18 PHE 17 -0.13 PRO 266

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: april 24th, 2026.

Should you encounter any unexpected behaviour, please let us know. elNémo has been relocated. **Some cleaning from time to time** Sorry for the inconvenience.

*** gluc-protot-model1 ***

CA distance fluctuations for 2610071411493079079

--- normal mode 25 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been relocated.
Some cleaning from time to time
Sorry for the inconvenience.

* gluc-protot-model1 *